Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethanesulfonic Acid SCHEMBL6561809 | 0.87 | ALDH1A1 (0.41) | ALDH1A1HSD11B1CYP1A1CYP1B1PKM | |
| 1-Hydroxy-3-Methoxybenzene SCHEMBL7085846 | 0.83 | CES2 (0.41) | PKMPTGS1CA1CA2 | |
| SCHEMBL27269877 | 0.73 | ALDH1A1 (0.65) | ALDH1A1CYP1A1CYP1B1NQO2CA1 | |
| SCHEMBL18812855 | 0.73 | ALDH1A1 (0.65) | ALDH1A1CYP1A1CYP1B1NQO2CA1 | |
| Trifluoromethanesulfonic Acid SCHEMBL7090348 | 0.73 | PTPN1 (0.34) | CA1 | |
| Trifluoromethanesulfonic Acid SCHEMBL7089707 | 0.73 | GABRA1 (0.39) | ALDH1A1HSD11B1 | |
| Anisole SCHEMBL4551224 | 0.72 | CA4 (0.56) | HSD11B1PKMGAACA1CA2 | |
| Trifluoromethanesulfonic Acid SCHEMBL23045290 | 0.71 | PKM (0.47) | ALDH1A1HSD11B1PKMGAACA1 | |
| 1-Hydroxy-3-Methoxybenzene SCHEMBL7085847 | 0.71 | KCNH2 (0.49) | ALDH1A1PTGS1CA1CA2 | |
| SCHEMBL1713657 | 0.71 | ALDH1A1 (0.48) | ALDH1A1HSD11B1CYP1A1CYP1B1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6624321-B2 | Metathesis ring-opening polymerization of cyclic ethers in the presence of catalysts such as aluminum bis(trifluoromethane-sulfonate) phenolate | BAYER AKTIENGESELLSCHAFT (DE) | 2003-09-23 | — | — | US | disclosed |
| US-20030097026-A1 | Process for the preparation of polyether polyols | DENNINGER UWE (DE) | 2003-05-22 | — | — | US | disclosed |
| US-6492565-B2 | USING ALKYLENE OXIDE IN PRESENCE OF LEWIS ACID CATALYST | BAYER AKTIENGESELLSCHAFT (DE) | 2002-12-10 | — | — | US | disclosed |
| US-20010053866-A1 | Process for the preparation of polyether polyols | BAYER AKTIENGESELLSCHAFT (DE) | 2001-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030097026-A1 | Process for the preparation of polyether polyols | PCBP1, FHIT, PUF60 | ALDH1A1 3594/4885HSD11B1 912/4885CYP1A1 619/4885 |
| US-20010053866-A1 | Process for the preparation of polyether polyols | PCBP1, FHIT, PUF60 | ALDH1A1 3594/4885HSD11B1 912/4885CYP1A1 619/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.