Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7095374 | 0.92 | IDO1 (0.42) | LMNATRPA1IDO1TDO2ALDH1A1 | |
| SCHEMBL7095932 | 0.85 | ALDH1A1 (0.46) | LMNATRPA1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL7093358 | 0.84 | LMNA (0.50) | LMNATRPA1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL7090779 | 0.73 | ESR1 (0.48) | LMNATRPA1IDO1TDO2ALDH1A1 | |
| SCHEMBL7092760 | 0.71 | HTR2A (0.43) | IDO1TDO2ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL7092758 | 0.69 | TRPM8 (0.41) | IDO1TDO2ALDH1A1SMN1; SMN2MTNR1A | |
| SCHEMBL6744566 | 0.67 | IDO1 (0.43) | TRPA1IDO1TDO2ALDH1A1TSHR | |
| SCHEMBL27449699 | 0.67 | SRC (0.42) | IDO1TDO2ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL9321120 | 0.67 | ALDH1A1 (0.46) | LMNAIDO1TDO2ALDH1A1SMN1; SMN2 | |
| SCHEMBL29634606 | 0.67 | ALDH1A1 (0.46) | LMNAIDO1TDO2ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003082777-A2 | NOVEL GLUCOCORTICOID RECEPTOR LIGANDS | KARO BIO AB (SE) | 2003-10-09 | — | — | WO | disclosed |