Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRA | P11474 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7103291 | 0.69 | TDP1 (0.38) | TSHRALDH1A1MAPTMAPK1PKM | |
| SCHEMBL7097377 | 0.68 | TDP1 (0.39) | TSHRALDH1A1MAPTPKMKDM4E | |
| SCHEMBL7100881 | 0.67 | ALDH1A1 (0.41) | TSHRALDH1A1MAPTGAAKDM4E | |
| SCHEMBL8478132 | 0.66 | TSHR (0.60) | TSHRALDH1A1MAPTGAAKDM4E | |
| SCHEMBL7103262 | 0.66 | SMN1; SMN2 (0.34) | ALDH1A1MAPTLMNAGAAKDM4E | |
| SCHEMBL7101713 | 0.65 | SMN1; SMN2 (0.33) | ALDH1A1MAPTLMNAGAAHPGD | |
| SCHEMBL7097291 | 0.65 | MAPT (0.35) | ALDH1A1MAPTMAPK1LMNAGAA | |
| SCHEMBL7100870 | 0.65 | HTT (0.42) | ALDH1A1LMNAHPGDKDM4EKMT2A | |
| SCHEMBL514833 | 0.64 | GPR35 (0.58) | TSHRALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL3311158 | 0.64 | DCTPP1 (0.39) | ALDH1A1MAPTLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030073850-A1 | 4-Imidazole derivatives of benzyl and restricted benzyl sulfonamides, sulfamides, ureas, carbamates, and amides and their use | ABBOTT LABORATORIES | 2003-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030073850-A1 | 4-Imidazole derivatives of benzyl and restricted benzyl sulfonamides, sulfamides, ureas, carbamates, and amides and their use | ADRA1D, ADRB1, ADRA1A | ESRRA 1104/4885TSHR 155/4885ALDH1A1 263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.