SCHEMBL710336

SCHEMBL710336

c1ccc(N(c2ccccc2)c2ccc(-c3ccc(-c4ccnc(Nc5ccc6ccccc6c5)n4)cc3)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SYK P43405 1/20 0.55
GSK3B P49841 3/20 0.54
DKK1 O94907 1/20 0.54
PIK3CG P48736 6/20 0.52
MAPK8 P45983 3/20 0.52
CAMKK2 Q96RR4 2/20 0.52
CAMK2D Q13557 3/20 0.50
IKBKB O14920 5/20 0.49
PIK3CA P42336 3/20 0.49
PIK3CB P42338 2/20 0.49
JAK2 O60674 1/20 0.49
JAK3 P52333 1/20 0.49
MAPK10 P53779 1/20 0.47
CDK5 Q00535 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL709831 0.89 IKBKB (0.59) GSK3BPIK3CGMAPK8CAMKK2CAMK2D
SCHEMBL710850 0.87 CAMK2D (0.63) GSK3BPIK3CGMAPK8CAMKK2CAMK2D
SCHEMBL709040 0.80 CYP2C9 (0.38) SYKGSK3BDKK1CAMK2DIKBKB
SCHEMBL12955830 0.79 ALDH1A1 (0.62)
SCHEMBL12956012 0.77 ALDH1A1 (0.65)
SCHEMBL10001570 0.75 ALDH1A1 (0.71)
SCHEMBL10019586 0.75 DYRK1A (0.41) GSK3BDKK1CAMK2DIKBKB
SCHEMBL13175109 0.74 ALDH1A1 (0.61)
SCHEMBL27113852 0.74 GSK3B (0.55) SYKGSK3BDKK1PIK3CGMAPK8
SCHEMBL7472770 0.73 ABL1 (0.67) GSK3BPIK3CGMAPK8CAMKK2CAMK2D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8124762-B2 Diphenyl amine derivatives having luminescence property KOREA INSTITUTE OF SCIENCE & TECHNOLOGY (KR) 2012-02-28 US disclosed
US-8124762-B2 Diphenyl amine derivatives having luminescence property KOREA INSTITUTE OF SCIENCE & TECHNOLOGY (KR) 2012-02-28 US disclosed
US-8124762-B2 Diphenyl amine derivatives having luminescence property KOREA INSTITUTE OF SCIENCE & TECHNOLOGY (KR) 2012-02-28 US disclosed
US-20100063281-A1 DIPHENYL AMINE DERIVATIVES HAVING LUMINESCENCE PROPERTY KOREA INSTITUTE OF SCIENCE & TECHNOLOGY (KR) 2010-03-11 US disclosed
US-20100063281-A1 DIPHENYL AMINE DERIVATIVES HAVING LUMINESCENCE PROPERTY KOREA INSTITUTE OF SCIENCE & TECHNOLOGY (KR) 2010-03-11 US disclosed
US-20100063281-A1 DIPHENYL AMINE DERIVATIVES HAVING LUMINESCENCE PROPERTY KOREA INSTITUTE OF SCIENCE & TECHNOLOGY (KR) 2010-03-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100063281-A1 DIPHENYL AMINE DERIVATIVES HAVING LUMINESCENCE PROPERTY TYR, PNMT, DDC SYK 2006/4885GSK3B 3680/4885DKK1 3150/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.