SCHEMBL710850

SCHEMBL710850

c1ccc(Nc2nccc(-c3ccc(-c4ccc(N(c5ccccc5)c5ccccc5)cc4)cc3)n2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CAMK2D Q13557 5/20 0.63
PRKCD Q05655 2/20 0.59
ABL1 P00519 1/20 0.59
EGFR P00533 1/20 0.59
PRKCA P17252 1/20 0.59
JAK2 O60674 3/20 0.59
JAK3 P52333 1/20 0.59
IKBKB O14920 6/20 0.55
MAPK8 P45983 3/20 0.55
PIK3CG P48736 3/20 0.55
GSK3B P49841 2/20 0.55
CAMKK2 Q96RR4 2/20 0.55
MAPK10 P53779 2/20 0.53
HDAC1 Q13547 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50
PIK3CA P42336 1/20 0.50
PIK3CB P42338 1/20 0.50
CHEK1 O14757 1/20 0.50
AURKA O14965 1/20 0.50
NPC1 O15118 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL709831 0.96 IKBKB (0.59) CAMK2DPRKCDABL1EGFRPRKCA
SCHEMBL710336 0.87 SYK (0.55) CAMK2DJAK2JAK3IKBKBMAPK8
SCHEMBL1593016 0.85 PRKCD (0.79) CAMK2DPRKCDABL1EGFRPRKCA
SCHEMBL4029958 0.80 ABL1 (0.72) CAMK2DPRKCDABL1EGFRPRKCA
SCHEMBL7472770 0.79 ABL1 (0.67) CAMK2DPRKCDABL1EGFRPRKCA
SCHEMBL10977837 0.77 PIK3CG (0.78) CAMK2DPRKCDABL1EGFRPRKCA
SCHEMBL3521444 0.77 CAMK2D (0.63) CAMK2DPRKCDABL1EGFRPRKCA
SCHEMBL710948 0.77 MAOA (0.38) CAMK2DJAK2JAK3MAPK8PIK3CG
SCHEMBL712182 0.76 HSP90AA1 (0.69) JAK3GSK3BAURKANPC1PDPK1
SCHEMBL3753567 0.75 IKBKB (0.68) CAMK2DPRKCDABL1EGFRPRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8124762-B2 Diphenyl amine derivatives having luminescence property KOREA INSTITUTE OF SCIENCE & TECHNOLOGY (KR) 2012-02-28 US disclosed
US-8124762-B2 Diphenyl amine derivatives having luminescence property KOREA INSTITUTE OF SCIENCE & TECHNOLOGY (KR) 2012-02-28 US disclosed
US-8124762-B2 Diphenyl amine derivatives having luminescence property KOREA INSTITUTE OF SCIENCE & TECHNOLOGY (KR) 2012-02-28 US disclosed
US-20100063281-A1 DIPHENYL AMINE DERIVATIVES HAVING LUMINESCENCE PROPERTY KOREA INSTITUTE OF SCIENCE & TECHNOLOGY (KR) 2010-03-11 US disclosed
US-20100063281-A1 DIPHENYL AMINE DERIVATIVES HAVING LUMINESCENCE PROPERTY KOREA INSTITUTE OF SCIENCE & TECHNOLOGY (KR) 2010-03-11 US disclosed
US-20100063281-A1 DIPHENYL AMINE DERIVATIVES HAVING LUMINESCENCE PROPERTY KOREA INSTITUTE OF SCIENCE & TECHNOLOGY (KR) 2010-03-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100063281-A1 DIPHENYL AMINE DERIVATIVES HAVING LUMINESCENCE PROPERTY TYR, PNMT, DDC CAMK2D 2043/4885PRKCD 4392/4885ABL1 37/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.