Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.35 |
| ▸ | CTSB | P07858 | 4/20 | 0.35 |
| ▸ | CTSS | P25774 | 4/20 | 0.35 |
| ▸ | CTSL | P07711 | 3/20 | 0.35 |
| ▸ | FABP4 | P15090 | 3/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.34 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL812375 | 0.87 | CTSL (0.40) | SMN1; SMN2OPRM1CTSBCTSSCTSL | |
| SCHEMBL6739957 | 0.86 | CTSL (0.39) | SMN1; SMN2OPRM1CTSBCTSSCTSL | |
| SCHEMBL8862966 | 0.80 | POLB (0.40) | SMN1; SMN2MEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8862797 | 0.80 | POLB (0.40) | SMN1; SMN2MEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8862538 | 0.80 | POLB (0.40) | SMN1; SMN2MEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8863072 | 0.79 | L3MBTL1 (0.41) | SMN1; SMN2OPRM1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9980974 | 0.77 | FPR2 (0.40) | SMN1; SMN2OPRM1MEN1KMT2AOPRD1 | |
| SCHEMBL14432207 | 0.76 | MAPT (0.42) | SMN1; SMN2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL1476383 | 0.76 | CTSB (0.39) | SMN1; SMN2OPRM1CTSBCTSSCTSL | |
| SCHEMBL3164180 | 0.72 | SMN1; SMN2 (0.34) | SMN1; SMN2OPRM1MEN1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030096806-A1 | Arylphenyl-substituted cyclic ketoenols | LIEB FOLKER (DE) | 2003-05-22 | — | — | US | disclosed |
| US-6451843-B1 | Arylphenyl-substituted cyclic keto enols | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030096806-A1 | Arylphenyl-substituted cyclic ketoenols | KCNE1, KCNQ3, SULT1E1 | SMN1; SMN2 4637/4885OPRM1 1231/4885CTSB 2710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.