Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.47 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL407090 | 0.83 | TDP1 (0.48) | ALDH1A1HIF1AVCAM1TDP1ATM | |
| SCHEMBL57882 | 0.80 | TSHR (0.40) | ALDH1A1TDP1ATMKMT2AMEN1 | |
| SCHEMBL4337113 | 0.79 | ALDH1A1 (0.31) | ALDH1A1HIF1A | |
| SCHEMBL6800906 | 0.78 | TDP1 (0.38) | ALDH1A1HIF1ATDP1KMT2AMEN1 | |
| SCHEMBL58127 | 0.77 | HSD17B10 (0.54) | ALDH1A1TDP1MAPTCYP3A4TSHR | |
| SCHEMBL1028967 | 0.77 | TDP1 (0.50) | ALDH1A1TDP1KMT2AMEN1MAPT | |
| SCHEMBL247495 | 0.75 | PARP1 (0.41) | ALDH1A1TDP1KMT2AMEN1MAPT | |
| SCHEMBL19859 | 0.75 | VCAM1 (0.46) | ALDH1A1VCAM1TDP1CYP3A4TSHR | |
| SCHEMBL232839 | 0.75 | TDP1 (0.39) | ALDH1A1TDP1KMT2AMEN1MAPT | |
| SCHEMBL2783828 | 0.75 | TDP1 (0.48) | ALDH1A1TDP1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 469 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016049595-A1 | HETEROARYL INHIBITORS OF PDE4 | Tetra Discovery Partners, LLC (US) | 2016-03-31 | — | — | WO | claimed |
| CN-105400769-A | Hybridoma cell strain for anticoagulation factor VIII monoclonal antibody | UNIV TSINGHUA | 2016-03-16 | — | — | CN | claimed |
| CN-105349524-A | Hybridomas cell strain of anti-human coagulation factor VII polyclonal antibody | UNIV TSINGHUA | 2016-02-24 | — | — | CN | claimed |
| CN-105349495-A | Hybridomas cell strain of anti-human coagulation factor IX monoclonal antibody | UNIV TSINGHUA | 2016-02-24 | — | — | CN | claimed |
| CN-105349496-A | Hybridomas cell strain of anti-human macroglobulin monoclonal antibody | UNIV TSINGHUA | 2016-02-24 | — | — | CN | claimed |
| CN-105349497-A | Hybridomas cell strain of anti-human alpha-antitrysin polyclonal antibody | UNIV TSINGHUA | 2016-02-24 | — | — | CN | claimed |
| US-9221761-B2 | Method for inhibition of deubiquitinating activity | VIVOLUX AB (SE) | 2015-12-29 | — | — | US | claimed |
| CN-103391935-B | Diaminopyrimidine derivatives and process for preparing same | Liu Hanyangxing (KR) | 2015-12-23 | — | — | CN | claimed |
| CN-102548970-B | Novel (6-oxo-1, 6-dihydropyrimidin-2-yl) amide derivatives, process for their preparation and their medical use as akt (pkb) phosphorylation inhibitors | SAI NUOFEI (FR) | 2015-11-25 | — | — | CN | claimed |
| CN-103402997-B | Diaminopyrimidine derivatives and process for preparing same | Liu Hanyangxing (KR) | 2015-08-26 | — | — | CN | claimed |
| WO-2003095396-A2 | N,N,-SUBSTITUTED S-ARYL-ISOTHIOUREAS, N,N,N'-SUBSTITUTED S-ARYL-ISOTHIOUREAS AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (US) | 2003-11-20 | — | — | WO | claimed |
| US-20030171330-A1 | Antibacterial compound | SANKYO COMPANY, LIMITED (JP) | 2003-09-11 | — | — | US | claimed |
| EP-1218343-A4 | PYRIDINE CARBOXAMIDE OR SULFONAMIDE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2003-06-18 | — | — | EP | claimed |
| CN-1382152-A | Novel A-500359 derivatives | SANKYO CO (JP) | 2002-11-27 | — | — | CN | claimed |
| EP-1218343-A1 | PYRIDINE CARBOXAMIDE OR SULFONAMIDE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION Bioscience AG (DE) | 2002-07-03 | — | — | EP | claimed |
| EP-1209166-A1 | NOVEL A-500359 DERIVATIVES | Sankyo Company, Limited (JP) | 2002-05-29 | — | — | EP | claimed |
| WO-2001025203-A1 | PYRIDINE CARBOXAMIDE OR SULFONAMIDE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2001-04-12 | — | — | WO | claimed |
| EP-0175973-B1 | SUPPORT MATERIAL FOR THE USE IN IMMUNOASSAYS | ORPEGEN Medizinisch-Molekularbiologische Forschungsgesellschaft m.b.H (DE) | 1989-11-08 | — | — | EP | claimed |
| EP-0012822-B1 | 3,4-DISUBSTITUTED 2-PHENYLIMINO-IMIDAZOLIDINES, THEIR ACID ADDITION SALTS, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND PROCESS FOR THEIR PRODUCTION | C.H. BOEHRINGER SOHN (DE) | 1982-12-01 | — | — | EP | claimed |
| EP-0012822-A1 | 3,4-Disubstituted 2-phenylimino-imidazolidines, their acid addition salts, pharmaceutical preparations containing them and process for their production | C.H. BOEHRINGER SOHN (DE) | 1980-07-09 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030171330-A1 | Antibacterial compound | TLR1, MPO, O60361 | ALDH1A1 356/4885HIF1A 190/4885VCAM1 1179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.