Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LIPE | Q05469 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11061527 | 0.78 | KMT2A (0.49) | NOTUMALDH1A1L3MBTL1MAPK1MEN1 | |
| SCHEMBL7101702 | 0.73 | CYP3A4 (0.43) | ALDH1A1L3MBTL1MAPK1MEN1KMT2A | |
| SCHEMBL7101705 | 0.73 | CYP3A4 (0.43) | ALDH1A1L3MBTL1MAPK1MEN1KMT2A | |
| SCHEMBL11128528 | 0.73 | EGFR (0.58) | NOTUMALDH1A1L3MBTL1MAPK1KMT2A | |
| SCHEMBL17948794 | 0.72 | LMNA (0.56) | NOTUMALDH1A1L3MBTL1MAPK1LMNA | |
| SCHEMBL12869921 | 0.72 | EGFR (0.60) | NOTUMALDH1A1L3MBTL1MAPK1KMT2A | |
| SCHEMBL13355673 | 0.71 | CTSL (0.56) | ALDH1A1 | |
| SCHEMBL12027639 | 0.71 | L3MBTL1 (0.56) | NOTUMALDH1A1L3MBTL1MAPK1LMNA | |
| SCHEMBL1177836 | 0.71 | ALDH1A1 (0.73) | NOTUMALDH1A1L3MBTL1MAPK1MEN1 | |
| SCHEMBL15450611 | 0.70 | NOTUM (0.52) | NOTUMALDH1A1L3MBTL1MAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030232820-A1 | Method for synthesizing oxazinones | WOLFE SAUL (CA) | 2003-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030232820-A1 | Method for synthesizing oxazinones | DHPS, HSD17B12, PNPO | NOTUM 1021/4885ALDH1A1 555/4885L3MBTL1 4591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.