SCHEMBL710344

SCHEMBL710344

CCCC=CCCC(=O)OCC

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1I2 O75469 1/20 0.55
PGR P06401 1/20 0.55
ADORA3 P0DMS8 1/20 0.55
PTGS2 P35354 1/20 0.55
PDE4D Q08499 1/20 0.55
ALDH1A1 P00352 4/20 0.51
CYP3A4 P08684 1/20 0.51
ALOX15 P16050 1/20 0.51
TSHR P16473 1/20 0.51
HSD17B10 Q99714 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
CYP1A2 P05177 1/20 0.47
MGAM O43451 1/20 0.46
GAA P10253 1/20 0.46
SI P14410 1/20 0.46
MGAM2 Q2M2H8 1/20 0.46
FAAH O00519 2/20 0.44
TRPA1 O75762 1/20 0.43
MGLL Q99685 1/20 0.41
MAPT P10636 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL710343 1.00 NR1I2 (0.55) NR1I2PGRADORA3PTGS2PDE4D
SCHEMBL3505842 1.00 NR1I2 (0.55) NR1I2PGRADORA3PTGS2PDE4D
SCHEMBL9183882 0.93 NR1I2 (0.60) NR1I2PGRADORA3PTGS2PDE4D
SCHEMBL9183887 0.93 NR1I2 (0.60) NR1I2PGRADORA3PTGS2PDE4D
SCHEMBL14899313 0.88 NR1I2 (0.71) NR1I2PGRADORA3PTGS2PDE4D
SCHEMBL7139688 0.88 PGR (0.61) NR1I2PGRADORA3PTGS2PDE4D
SCHEMBL7139692 0.88 PGR (0.61) NR1I2PGRADORA3PTGS2PDE4D
SCHEMBL11467654 0.87 ADORA3 (0.70) NR1I2PGRADORA3PTGS2PDE4D
SCHEMBL16994601 0.87 ADORA3 (0.70) NR1I2PGRADORA3PTGS2PDE4D
SCHEMBL11467652 0.87 ADORA3 (0.70) NR1I2PGRADORA3PTGS2PDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3809876-A1 PROTECTIVE AGENT FOR FOOD PRODUCTS AND THE LIKE AND FOR CURING AND/OR STORAGE ROOMS OF THE SAME PERPRIN S.R.L. (IT) 2021-04-28 EP claimed
WO-2019243869-A1 PROTECTIVE AGENT FOR FOOD PRODUCTS AND THE LIKE AND FOR CURING AND/OR STORAGE ROOMS OF THE SAME PERPRIN S.R.L. (IT) 2019-12-26 WO claimed
WO-2025121408-A1 PERFUME COMPOSITION 高砂香料工業株式会社 2025-06-12 WO disclosed
US-20240108040-A1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2024-04-04 US disclosed
US-11758933-B2 High intensity sweeteners FIRMENICH INCORPORATED (US) 2023-09-19 US disclosed
CN-114539088-B Preparation method of oseltamivir 浙江工业大学 2023-06-23 CN disclosed
CN-116082237-A Nitrogen-containing heterocyclic compound and preparation method thereof 安徽中医药大学 2023-05-09 CN disclosed
EP-3368542-B1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2022-06-22 EP disclosed
US-11357246-B2 High intensity sweeteners FIRMENICH INCORPORATED (US) 2022-06-14 US disclosed
CN-114539088-A Preparation method of oseltamivir 浙江工业大学 2022-05-27 CN disclosed
US-20210227863-A1 HIGH INTENSITY SWEETENERS SENOMYX, INC. 2021-07-29 US disclosed
US-20170096418-A1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 FIRMENICH INCORPORATED 2017-04-06 US disclosed
US-20170087199-A1 COMPOSITIONS FOR DELIVERING A COOLING SENSATION SENOMYX INC (US) 2017-03-30 US disclosed
US-20160376263-A1 BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF SENOMYX INC (US) 2016-12-29 US disclosed
US-8124629-B2 Naphthylacetic acids HOFFMANN-LA ROCHE INC. (US) 2012-02-28 US disclosed
EP-2346807-A1 NAPHTHYLACETIC ACIDS F. Hoffmann-La Roche AG (CH) 2011-07-27 EP disclosed
US-20100137250-A1 NAPHTHYLACETIC ACIDS FIROOZNIA FARIBORZ 2010-06-03 US disclosed
WO-2010055005-A1 NAPHTHYLACETIC ACIDS F. HOFFMANN-LA ROCHE AG (CH) 2010-05-20 WO disclosed
US-4234741-A BENZENESELENYL HALIDE REACTANT, SELENIUM-CONTAINING INTERMEDIATES FIRMENICH, S.A. (CH) 1980-11-18 US disclosed
US-3953377-A Ethyl-2-trans-4-cis undecadienoate, ethyl-2-trans-4-cis dodecadienoate and ethyl-2-decadienoate perfume compositions FIRMENICH S.A. (CH) 1976-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240108040-A1 HIGH INTENSITY SWEETENERS TAS2R40, TAS2R60, TAS1R1 NR1I2 3388/4885PGR 4769/4885ADORA3 2392/4885
US-20100137250-A1 NAPHTHYLACETIC ACIDS HRH2, HRH1, HRH3 NR1I2 55/4885PGR 564/4885ADORA3 210/4885
US-20160376263-A1 BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF TAS2R5, TAS1R1, TAS2R1 NR1I2 1429/4885PGR 2815/4885ADORA3 666/4885
US-11357246-B2 High intensity sweeteners TAS2R40, TAS2R60, TAS1R1 NR1I2 3388/4885PGR 4769/4885ADORA3 2392/4885
US-20170087199-A1 COMPOSITIONS FOR DELIVERING A COOLING SENSATION TRPA1, PDE6G, PDE6D NR1I2 1269/4885PGR 1531/4885ADORA3 956/4885
US-20210227863-A1 HIGH INTENSITY SWEETENERS TAS2R40, TAS2R60, TAS1R1 NR1I2 3388/4885PGR 4769/4885ADORA3 2392/4885
US-11758933-B2 High intensity sweeteners TAS2R40, TAS2R60, TAS1R1 NR1I2 3388/4885PGR 4769/4885ADORA3 2392/4885
US-20170096418-A1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 TRPM8, TRPM6, TRPM4 NR1I2 2303/4885PGR 3399/4885ADORA3 1057/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.