Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ALPG | P10696 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL9790238 | 0.90 | DNM1 (0.47) | ALPLPOLBALPGALDH1A1KDM4E | |
| Acetic Acid SCHEMBL593316 | 0.88 | ALDH1A1 (0.68) | ALPLPOLBALPGALDH1A1KDM4E | |
| Acetic Acid SCHEMBL23069549 | 0.87 | DNM1 (0.49) | ALPLPOLBALPGALDH1A1KDM4E | |
| Acetic Acid SCHEMBL5720121 | 0.86 | ALDH1A1 (0.44) | ALPLPOLBALPGALDH1A1KDM4E | |
| Acetic Acid SCHEMBL22117370 | 0.85 | ALPL (0.48) | ALPLPOLBALPGALDH1A1KDM4E | |
| Acetic Acid SCHEMBL28732413 | 0.84 | DNM1 (0.54) | ALPLPOLBALPGALDH1A1KDM4E | |
| Acetic Acid SCHEMBL23069469 | 0.84 | ALPL (0.46) | ALPLPOLBALPGALDH1A1KDM4E | |
| SCHEMBL374778 | 0.84 | ALDH1A1 (0.67) | ALDH1A1KDM4ETDP1DNM1MEN1 | |
| Bicarbonate SCHEMBL29006716 | 0.84 | DNM1 (0.49) | ALPLPOLBALPGALDH1A1KDM4E | |
| Acetic Acid SCHEMBL22188514 | 0.82 | ALPL (0.47) | ALPLPOLBALPGALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260109817-A1 | FILM-FORMING ORGANOPOLYSILOXANE EMULSION COMPOSITION AND PRODUCTION METHOD THEREOF | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2026-04-23 | — | — | US | disclosed |
| EP-4603554-A1 | EMULSION COMPOSITION OF FILM-FORMING ORGANOPOLYSILOXANE AND PRODUCTION METHOD THEREFOR | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2025-08-20 | — | — | EP | disclosed |
| CN-119998417-A | Emulsion composition of film-forming organopolysiloxane and method for producing same | 信越化学工业株式会社 | 2025-05-13 | — | — | CN | disclosed |
| US-20030233008-A1 | Process for the preparation of carboxylic benzyl esters | BAYER AKTIENGESELLSCHAFT (DE) | 2003-12-18 | — | — | US | disclosed |
| EP-1371627-A1 | Process for the preparation of carboxylic acid benzyl esters | Bayer Aktiengesellschaft (DE) | 2003-12-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030233008-A1 | Process for the preparation of carboxylic benzyl esters | CPS1, BCAT2, BCAT1 | ALPL 1821/4885POLB 1014/4885ALPG 2773/4885 |
| US-20260109817-A1 | FILM-FORMING ORGANOPOLYSILOXANE EMULSION COMPOSITION AND PRODUCTION METHOD THEREOF | COL2A1, COL1A1, SMCHD1 | ALPL 194/4885POLB 874/4885ALPG 458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.