Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 9/20 | 1.00 |
| ▸ | OPRD1 | P41143 | 4/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7102313 | 0.85 | OPRK1 (1.00) | OPRK1OPRD1KMT2AMEN1LMNA | |
| SCHEMBL7106355 | 0.76 | OPRK1 (1.00) | OPRK1OPRD1MAPTLMNA | |
| SCHEMBL7101012 | 0.76 | OPRK1 (1.00) | OPRK1OPRD1LMNA | |
| SCHEMBL7101712 | 0.75 | OPRK1 (1.00) | OPRK1OPRD1KMT2A | |
| SCHEMBL1709278 | 0.74 | MEN1 (0.57) | OPRK1OPRD1KMT2AMEN1MAPT | |
| SCHEMBL7108642 | 0.73 | OPRK1 (1.00) | OPRK1OPRD1KMT2AMEN1 | |
| SCHEMBL14108276 | 0.72 | OPRD1 (0.55) | OPRK1OPRD1KMT2AMEN1MAPT | |
| SCHEMBL7106987 | 0.71 | OPRK1 (0.73) | OPRK1OPRD1MTNR1A | |
| SCHEMBL14153985 | 0.71 | RIPK1 (0.65) | OPRK1OPRD1KMT2AMEN1MAPT | |
| SCHEMBL6380046 | 0.69 | MEN1 (0.57) | OPRK1OPRD1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1055665-B1 | 3-(3-Hydroxyphenyl)-3-amino-propionamide derivatives | PFIZER PROD INC (US) | 2003-10-22 | — | — | EP | disclosed |
| EP-1055665-A1 | 3-(3-Hydroxyphenyl)-3-amino-propionamide derivatives | Pfizer Products Inc. (US) | 2000-11-29 | — | — | EP | disclosed |