Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 7/20 | 0.34 |
| ▸ | TUBB | P07437 | 7/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 7/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 7/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 7/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 7/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 7/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 7/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 7/20 | 0.34 |
| ▸ | TUBA3E | Q6PEY2 | 7/20 | 0.34 |
| ▸ | TUBA1A | Q71U36 | 7/20 | 0.34 |
| ▸ | TUBA1C | Q9BQE3 | 7/20 | 0.34 |
| ▸ | TUBB6 | Q9BUF5 | 7/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7448035 | 0.78 | TUBB4A (0.36) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9110854 | 0.78 | ALDH1A1 (0.36) | MAPTTSHRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL10833235 | 0.72 | KDM4E (0.36) | MAPTTSHRSMN1; SMN2TP53MEN1 | |
| SCHEMBL7446479 | 0.72 | MAPT (0.35) | MAPTTSHRDRD2RAB9ANPC1 | |
| SCHEMBL26259813 | 0.72 | DRD2 (0.41) | MAPTTSHRDRD2RAB9ANPC1 | |
| SCHEMBL7106296 | 0.70 | TUBB4A (0.36) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL27850505 | 0.69 | MAPT (0.44) | MAPTTSHRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7107269 | 0.69 | SMPD3 (0.39) | MAPTTSHRRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6033035 | 0.66 | HTR2A (0.38) | MAPTTSHRMEN1KMT2ABLM | |
| SCHEMBL557929 | 0.64 | KEAP1 (0.44) | MAPTRAB9ANPC1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030008901-A1 | Hydroxy pipecolate hydroxamic acid derivatives | MCCLURE KIM F (US) | 2003-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030008901-A1 | Hydroxy pipecolate hydroxamic acid derivatives | MMP1, MMP10, MMP3 | MAPT 3237/4885TSHR 4266/4885DRD2 1374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.