Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 10/20 | 1.00 |
| ▸ | OPRD1 | P41143 | 5/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7101012 | 0.94 | OPRK1 (1.00) | OPRK1OPRD1ITGB3ITGA2B | |
| SCHEMBL7107673 | 0.87 | OPRK1 (0.77) | OPRK1OPRD1 | |
| SCHEMBL7106587 | 0.81 | OPRK1 (0.76) | OPRK1OPRD1MEN1KMT2A | |
| SCHEMBL7102313 | 0.78 | OPRK1 (1.00) | OPRK1OPRD1MEN1KMT2A | |
| SCHEMBL7106355 | 0.76 | OPRK1 (1.00) | OPRK1OPRD1NPC1 | |
| SCHEMBL7101712 | 0.74 | OPRK1 (1.00) | OPRK1OPRD1KMT2AEPHX2 | |
| SCHEMBL7106526 | 0.73 | OPRK1 (1.00) | OPRK1OPRD1MEN1KMT2A | |
| SCHEMBL22972218 | 0.70 | MEN1 (0.74) | OPRK1OPRD1MEN1KMT2ANPC1 | |
| SCHEMBL1709299 | 0.68 | EPHX1 (0.57) | OPRK1OPRD1KMT2ANPC1HDAC6 | |
| SCHEMBL19652077 | 0.68 | EPHX1 (0.57) | OPRK1OPRD1KMT2ANPC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1055665-B1 | 3-(3-Hydroxyphenyl)-3-amino-propionamide derivatives | PFIZER PROD INC (US) | 2003-10-22 | — | — | EP | disclosed |
| EP-1055665-A1 | 3-(3-Hydroxyphenyl)-3-amino-propionamide derivatives | Pfizer Products Inc. (US) | 2000-11-29 | — | — | EP | disclosed |