SCHEMBL711267

SCHEMBL711267

CN(C)c1ccc2c(ccc3ccccc32)c1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 3/20 0.52
MCL1 Q07820 1/20 0.47
EP300 Q09472 1/20 0.47
KAT2B Q92831 1/20 0.47
KAT8 Q9H7Z6 1/20 0.47
TDP1 Q9NUW8 2/20 0.44
ALDH1A1 P00352 2/20 0.44
CYP2A6 P11509 1/20 0.44
TSHR P16473 1/20 0.44
HSD17B10 Q99714 1/20 0.44
PTPN22 Q9Y2R2 1/20 0.44
MAPT P10636 2/20 0.42
KDM4E B2RXH2 1/20 0.42
SIGMAR1 Q99720 1/20 0.42
CHEK1 O14757 1/20 0.40
NEK2 P51955 1/20 0.40
LIMK1 P53667 1/20 0.40
DYRK1A Q13627 1/20 0.40
CLK4 Q9HAZ1 1/20 0.40
HPGD P15428 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29974868 1.00 HPRT1 (0.52) HPRT1MCL1EP300KAT2BKAT8
SCHEMBL235342 0.90 EP300 (0.57) MCL1EP300KAT2BKAT8TDP1
SCHEMBL31016039 0.79 HPRT1 (0.58) HPRT1MCL1EP300KAT2BKAT8
SCHEMBL8585842 0.79 HPRT1 (0.58) HPRT1MCL1EP300KAT2BKAT8
SCHEMBL27326675 0.77 TRPM4 (0.53) HPRT1MCL1EP300KAT2BKAT8
SCHEMBL15911005 0.75 HPRT1 (0.58) HPRT1TDP1ALDH1A1CYP2A6TSHR
SCHEMBL25411566 0.74 HPRT1 (0.64) HPRT1TDP1ALDH1A1CYP2A6TSHR
SCHEMBL888244 0.74 PTPN22 (0.78) HPRT1TDP1ALDH1A1CYP2A6TSHR
Chrysene-1,2-Diol SCHEMBL30621738 0.74 PTPN22 (0.78) HPRT1TDP1ALDH1A1CYP2A6TSHR
Chrysene-1,2-Diol SCHEMBL4543236 0.74 PTPN22 (0.78) HPRT1TDP1ALDH1A1CYP2A6TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106726623-B Single-component photocuring composite material with fluoride ion release characteristic for dental restoration and application thereof 日照沪鸽生物材料有限公司 2020-12-04 CN claimed
EP-3861977-B1 (METH)ACRYLATE, MONOMER COMPOSITION, MOLDED BODY, COMPOSITION FOR DENTAL MATERIAL, AND DENTAL MATERIAL MITSUI CHEMICALS INC (JP) 2026-05-06 EP disclosed
US-12441821-B2 (Meth)acrylate and use thereof MITSUI CHEMICALS, INC. (JP) 2025-10-14 US disclosed
EP-4556495-A1 CURABLE COMPOSITION, CURED PRODUCT, AND DENTAL MATERIAL Mitsui Chemicals, Inc. (JP) 2025-05-21 EP disclosed
US-20250122315-A1 (METH)ACRYLATE AND USE THEREOF MITSUI CHEMICALS, INC. (JP) 2025-04-17 US disclosed
US-12275814-B2 (Meth)acrylate, monomer composition, molded body, composition for dental material, and dental material MITSUI CHEMICALS, INC. (JP) 2025-04-15 US disclosed
EP-3719043-B1 (METH)ACRYLATE, MONOMER COMPOSITION, DENTAL MATERIAL OBTAINED FROM SAID COMPOSITION, AND PRODUCTION METHOD THEREOF MITSUI CHEMICALS INC (JP) 2024-11-13 EP disclosed
EP-3603606-B1 ADHESIVE MONOMER FOR DENTAL MATERIAL MITSUI CHEMICALS INC (JP) 2024-11-13 EP disclosed
EP-3586814-B1 DENTAL CURABLE COMPOSITION G C DENTAL IND CORP (JP) 2024-01-31 EP disclosed
EP-3604318-B1 PHOSPHORUS-CONTAINING COMPOUND MITSUI CHEMICALS INC (JP) 2024-01-17 EP disclosed
EP-3135270-A1 POLYMERIZABLE MONOMER FOR DENTAL MATERIAL Mitsui Chemicals, Inc. (JP) 2017-03-01 EP disclosed
EP-2123247-B1 CURABLE COMPOSITION FOR DENTAL PURPOSES KURARAY NORITAKE DENTAL INC (JP) 2016-08-17 EP disclosed
US-20150320646-A1 DENTAL CURABLE COMPOSITION AND DENTAL FLOWABLE COMPOSITE RESIN KURARAY NORITAKE DENTAL INC. (JP) 2015-11-12 US disclosed
EP-2926796-A1 DENTAL CURABLE COMPOSITION AND DENTAL FLOWABLE COMPOSITE RESIN Kuraray Noritake Dental Inc. (JP) 2015-10-07 EP disclosed
US-8124669-B2 Dental composition KURARAY MEDICAL INC. (JP) 2012-02-28 US disclosed
US-7951851-B2 Curable composition for dental purposes KURARAY MEDICAL INC. (JP) 2011-05-31 US disclosed
US-20110003267-A1 DENTAL COMPOSITION KURARAY MEDICAL INC. (JP) 2011-01-06 US disclosed
US-20100105802-A1 CURABLE COMPOSITION FOR DENTAL PURPOSES KURARAY MEDICAL INC. (JP) 2010-04-29 US disclosed
EP-2123247-A1 CURABLE COMPOSITION FOR DENTAL PURPOSES Kuraray Medical Inc. (JP) 2009-11-25 EP disclosed
EP-2119425-A1 DENTAL COMPOSITION Kuraray Medical Inc. (JP) 2009-11-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100105802-A1 CURABLE COMPOSITION FOR DENTAL PURPOSES H1-0, H1-3, H1-2 HPRT1 2806/4885MCL1 4335/4885EP300 1466/4885
US-20250122315-A1 (METH)ACRYLATE AND USE THEREOF TST, MMAB, BHMT2 HPRT1 123/4885MCL1 1331/4885EP300 3048/4885
US-12275814-B2 (Meth)acrylate, monomer composition, molded body, composition for dental material, and dental material MMAB, CAD, ALG3 HPRT1 401/4885MCL1 3152/4885EP300 1803/4885
US-12441821-B2 (Meth)acrylate and use thereof TST, MMAB, BHMT2 HPRT1 123/4885MCL1 1331/4885EP300 3048/4885
US-20110003267-A1 DENTAL COMPOSITION NLRP3, TAS2R42, CAD HPRT1 175/4885MCL1 4788/4885EP300 2133/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.