Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 6/20 | 0.40 |
| ▸ | ABCC1 | P33527 | 5/20 | 0.40 |
| ▸ | CTSA | P10619 | 4/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15031958 | 0.72 | KIT (0.46) | ABCB1ABCC1KITERN1 | |
| SCHEMBL6859292 | 0.72 | ADRA2A (0.51) | ADRA2AADRA1ACYP2D6MEN1MAPK1 | |
| SCHEMBL12325928 | 0.72 | CFD (0.54) | ABCB1ABCC1MAPK1 | |
| SCHEMBL6858942 | 0.72 | GABRA1 (0.41) | ADRA2AADRA1ACYP2D6MEN1MAPK1 | |
| SCHEMBL15010355 | 0.71 | ENPP2 (0.44) | ABCB1ABCC1KITERN1 | |
| SCHEMBL4311992 | 0.71 | ACHE (0.56) | ADRA2AADRA1ACYP2D6MEN1MAPK1 | |
| SCHEMBL17388712 | 0.71 | ADRA1A (0.68) | ADRA2AADRA1ACYP2D6MEN1MAPK1 | |
| SCHEMBL15011357 | 0.70 | KIT (0.44) | ABCB1ABCC1KITERN1 | |
| SCHEMBL16311804 | 0.70 | ABCB1 (0.43) | ABCB1ABCC1KITERN1 | |
| SCHEMBL6858946 | 0.70 | CTSA (0.44) | CTSAADRA2AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6638646-B2 | Polymerizing one or more monomers containing dihalogen containing substituted biaryls, via a base-induced dehydrohalogenation | SEMICONDUCTORS GMBH (DE) | 2003-10-28 | — | — | US | disclosed |
| US-20030088050-A1 | Substituted poly(arylenevinylenes), process for their preparation, and their use in electroluminescent elements | MERCK PATENT GMBH (DE) | 2003-05-08 | — | — | US | disclosed |
| US-20020064680-A1 | Substituted poly(arylene vinylenes), method for producing the same, and their use in electroluminescent elements | AXIVA GMBH (DE) | 2002-05-30 | — | — | US | disclosed |