SCHEMBL7112971

SCHEMBL7112971

O=S(=O)(c1ccc(-c2ccc(Br)cc2)cc1)N(c1ccc(OCC2CCN(c3ccncc3)CC2)cc1)S(=O)(=O)c1ccc(-c2ccc(Br)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
F10 P00742 6/20 0.45
LSS P48449 1/20 0.45
RORC P51449 1/20 0.40
HRH1 P35367 3/20 0.38
HRH3 Q9Y5N1 3/20 0.38
HRH2 P25021 2/20 0.37
GPR119 Q8TDV5 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7118163 0.89 F10 (0.44) F10LSS
SCHEMBL6576136 0.84 CYP3A4 (0.47) F10LSS
SCHEMBL7115221 0.77 MAPT (0.43) F10LSSRORCHRH1HRH3
SCHEMBL5632390 0.75 ALDH1A1 (0.45) F10HRH1HRH3HRH2
SCHEMBL6578432 0.75 F10 (0.46) F10LSS
SCHEMBL7119668 0.74 F10 (0.42) F10LSS
SCHEMBL5632401 0.72 F10 (0.55) F10HRH1HRH3HRH2
SCHEMBL7119420 0.72 MAPT (0.45) F10RORCHRH1HRH3
SCHEMBL9761106 0.71 SIGMAR1 (0.64) F10HRH3
SCHEMBL9759900 0.71 ADRB1 (0.52) F10HRH1HRH3HRH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030207882-A1 Aminoheterocyclic derivatives as antithrombotic or anticoagulant agents ZENECA LIMITED 2003-11-06 US claimed
US-20030207882-A1 Aminoheterocyclic derivatives as antithrombotic or anticoagulant agents ZENECA LIMITED 2003-11-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030207882-A1 Aminoheterocyclic derivatives as antithrombotic or anticoagulant agents F2, SERPINC1, F11 F10 8/4885LSS 608/4885RORC 3128/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.