Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.33 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.33 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.33 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14354527 | 0.81 | ALDH1A1 (0.50) | ALDH1A1LMNASMN1; SMN2HTTKIF11 | |
| SCHEMBL20812179 | 0.78 | ALDH1A1 (0.56) | ALDH1A1LMNASMN1; SMN2HTTKIF11 | |
| SCHEMBL152444 | 0.74 | HTR6 (0.52) | ALDH1A1SMN1; SMN2TDP1KMT2AGAA | |
| Benzene SCHEMBL8203386 | 0.74 | HTR6 (0.52) | ALDH1A1SMN1; SMN2TDP1KMT2AGAA | |
| SCHEMBL1148423 | 0.74 | LMNA (0.38) | ALDH1A1LMNAMAPTPTGS1PTGS2 | |
| SCHEMBL7114609 | 0.73 | NAPRT (0.59) | ALDH1A1MAPTPTGS2NFE2L2SMN1; SMN2 | |
| SCHEMBL5403737 | 0.72 | CA2 (0.54) | ALDH1A1HTTCA1CA2 | |
| SCHEMBL14194251 | 0.71 | KIF11 (0.53) | ALDH1A1MAPTPTGS1PTGS2KIF11 | |
| SCHEMBL3945757 | 0.70 | LMNA (0.40) | ALDH1A1LMNAMAPTNFE2L2SMN1; SMN2 | |
| SCHEMBL1134359 | 0.70 | ALDH1A1 (0.57) | ALDH1A1LMNAMAPTPTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7189500-B2 | Photothermographic image-recording material | FUJI PHOTO FILM CO., LTD. (JP) | 2007-03-13 | — | — | US | disclosed |
| US-7189500-B2 | Photothermographic image-recording material | FUJI PHOTO FILM CO., LTD. (JP) | 2007-03-13 | — | — | US | disclosed |
| EP-1361214-A1 | Process for preparing methylthiopyridine | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2003-11-12 | — | — | EP | disclosed |
| EP-1184375-B1 | PROCESS FOR PREPARING TRIBROMOMETHYLSULFONYLPYRIDINE | SUMITOMO SEIKA CHEMICALS (JP) | 2003-10-29 | — | — | EP | disclosed |
| US-6509470-B2 | Reacting a methylthiopyridine and a hypobromite in the presence of a base and water in a heterogeneous system to form tribromomethylsufonylpyridine | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2003-01-21 | — | — | US | disclosed |
| US-20020128484-A1 | Process for preparing tribromomethylsulfonylpyridine | FUJISAWA EIJI (JP) | 2002-09-12 | — | — | US | disclosed |
| US-6420564-B1 | REACTION OF METHYLTHIOPYRIDINE AND HYPOBROMITE IN WATER AND BASE | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2002-07-16 | — | — | US | disclosed |
| EP-1184375-A1 | PROCESS FOR PREPARING TRIBROMOMETHYLSULFONYLPYRIDINE | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2002-03-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020128484-A1 | Process for preparing tribromomethylsulfonylpyridine | SKP1, TPMT, TET2 | ALDH1A1 4235/4885LMNA 3792/4885MAPT 2589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.