SCHEMBL1148423

SCHEMBL1148423

O=S(=O)(Br)c1ccncc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.38
MAPT P10636 2/20 0.38
ALDH1A1 P00352 2/20 0.36
PTGS1 P23219 1/20 0.36
PTGS2 P35354 1/20 0.36
NFE2L2 Q16236 1/20 0.36
SMN1; SMN2 Q16637 3/20 0.35
KMT2A Q03164 3/20 0.35
MEN1 O00255 2/20 0.35
CYP2D6 P10635 2/20 0.35
HDAC8 Q9BY41 1/20 0.35
CHRM1 P11229 1/20 0.35
TSHR P16473 1/20 0.35
MAPK1 P28482 1/20 0.35
KCNA1 Q09470 1/20 0.35
NAPRT Q6XQN6 1/20 0.35
NPC1 O15118 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
GAA P10253 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8779885 0.78 CA2 (0.41) LMNAALDH1A1TSHRMAPK1CA1
SCHEMBL3945757 0.74 LMNA (0.40) LMNAMAPTALDH1A1NFE2L2SMN1; SMN2
SCHEMBL1134359 0.74 ALDH1A1 (0.57) LMNAMAPTALDH1A1PTGS1PTGS2
SCHEMBL7113014 0.74 ALDH1A1 (0.37) LMNAMAPTALDH1A1PTGS1PTGS2
SCHEMBL2377128 0.72 ENPP2 (0.50) ALDH1A1PTGS1PTGS2SMN1; SMN2CYP3A4
SCHEMBL16977343 0.72 HDAC8 (0.41) LMNAMAPTALDH1A1NFE2L2SMN1; SMN2
SCHEMBL2495302 0.72 NFE2L2 (0.40) LMNAMAPTALDH1A1NFE2L2SMN1; SMN2
SCHEMBL28783303 0.72 TSHR (0.55) LMNAMAPTALDH1A1SMN1; SMN2CYP2D6
SCHEMBL30429065 0.72 F2 (0.41) LMNAMAPTALDH1A1PTGS2NFE2L2
SCHEMBL2377123 0.72 LMNA (0.38) LMNAMAPTALDH1A1NFE2L2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8481744-B2 Process for producing anthranilamide compound ISHIHARA SANGYO KAISHA, LTD. (JP) 2013-07-09 US disclosed
EP-2264021-B1 PROCESS FOR PRODUCING AN ANTHRANILAMIDE COMPOUND ISHIHARA SANGYO KAISHA (JP) 2013-06-26 EP disclosed
US-20110034696-A1 PROCESS FOR PRODUCING ANTHRANILAMIDE COMPOUND ISHIHARA SANGYO KAISHA, LTD. (JP) 2011-02-10 US disclosed
EP-2264021-A1 PROCESS FOR PRODUCING AN ANTHRANILAMIDE COMPOUND ISHIHARA SANGYO KAISHA, LTD. (JP) 2010-12-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110034696-A1 PROCESS FOR PRODUCING ANTHRANILAMIDE COMPOUND SQOR, NOX5, NOX3 LMNA 3101/4885MAPT 4184/4885ALDH1A1 819/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.