Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLPP | Q16740 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.45 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.45 |
| ▸ | WDR5 | P61964 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL714409 | 0.80 | HDAC6 (0.43) | SMN1; SMN2WDR5LMNA | |
| SCHEMBL3059734 | 0.79 | SCN9A (0.43) | MAPTRAB9AGAALMNA | |
| SCHEMBL15358859 | 0.77 | AKR1C2 (0.59) | CLPPSMN1; SMN2AKR1C2AKR1C1VCAM1 | |
| SCHEMBL2554714 | 0.76 | AKR1C2 (0.54) | CLPPSMN1; SMN2AKR1C2AKR1C1WDR5 | |
| SCHEMBL13753322 | 0.75 | AKR1C2 (0.51) | CLPPSMN1; SMN2AKR1C2AKR1C1IRAK4 | |
| SCHEMBL711773 | 0.75 | HDAC6 (0.42) | ALDH1A1LMNA | |
| SCHEMBL3049404 | 0.74 | FLT1 (0.41) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL711275 | 0.73 | HDAC6 (0.41) | SMN1; SMN2WDR5MAPTMEN1MAPK1 | |
| SCHEMBL4302375 | 0.73 | PDK1 (0.52) | CLPPSMN1; SMN2AKR1C2AKR1C1VCAM1 | |
| SCHEMBL3585691 | 0.73 | LMNA (0.56) | SMN1; SMN2AKR1C2AKR1C1VCAM1IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120310010-A1 | Method for producing sulfonamides | BASF SE (DE) | 2012-12-06 | — | — | US | disclosed |
| US-8263806-B2 | Method for producing sulfonamides | BASF SE (DE) | 2012-09-11 | — | — | US | disclosed |
| US-20100228054-A1 | Method for Producing Sulfonamides | BASF SE (DE) | 2010-09-09 | — | — | US | disclosed |
| EP-1957443-A2 | METHOD FOR PRODUCING SULFONAMIDES | BASF SE (DE) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007063028-A2 | METHOD FOR PRODUCING SULFONAMIDES | BASF SE (DE) | 2007-06-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100228054-A1 | Method for Producing Sulfonamides | STS, MSRB3, SQOR | CLPP 4716/4885SMN1; SMN2 1212/4885AKR1C2 546/4885 |
| US-20120310010-A1 | Method for producing sulfonamides | MSRB3, STS, TST | CLPP 4346/4885SMN1; SMN2 1196/4885AKR1C2 1682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.