Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 8/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.42 |
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MAOA | P21397 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10939607 | 0.78 | MAOA (0.42) | ALDH1A1POLBMAPTMAPK1MEN1 | |
| SCHEMBL8121267 | 0.75 | DPP4 (0.42) | ALDH1A1POLBDPP4MAPTMEN1 | |
| SCHEMBL17576233 | 0.73 | ALDH1A1 (0.42) | ALDH1A1POLBMAPTMAPK1MEN1 | |
| SCHEMBL3860252 | 0.72 | DPP4 (0.62) | ALDH1A1POLBDPP4MAPTMEN1 | |
| SCHEMBL2396625 | 0.72 | ALDH1A1 (0.44) | ALDH1A1POLBMAPTMAPK1MEN1 | |
| Anthraquinone SCHEMBL28686015 | 0.72 | IDO1 (0.55) | ALDH1A1POLBRXFP1MAPTMAPK1 | |
| SCHEMBL13735962 | 0.71 | MEN1 (0.47) | ALDH1A1POLBRXFP1MAPTMAPK1 | |
| SCHEMBL16134542 | 0.71 | TERT (0.44) | ALDH1A1POLBMAPTMAPK1MEN1 | |
| SCHEMBL17702673 | 0.71 | ALDH1A1 (0.45) | ALDH1A1POLBMAPTMAPK1MEN1 | |
| SCHEMBL16134473 | 0.68 | L3MBTL1 (0.49) | ALDH1A1POLBMAPTMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124637-B2 | Anthra [1, 2-d]imidazole-6,11-dione derivatives, preparation method and application thereof | NATIONAL DEFENSE MEDICAL CENTER (TW) | 2012-02-28 | — | — | US | disclosed |
| US-8124637-B2 | Anthra [1, 2-d]imidazole-6,11-dione derivatives, preparation method and application thereof | NATIONAL DEFENSE MEDICAL CENTER (TW) | 2012-02-28 | — | — | US | disclosed |
| US-8067454-B2 | Thio-substituted Anthra [1, 2-d] imidazole- 6, 11-dione derivatives, preparation method and application thereof | NATIONAL DEFENSE MEDICAL CENTER (TW) | 2011-11-29 | — | — | US | disclosed |
| US-8067454-B2 | Thio-substituted Anthra [1, 2-d] imidazole- 6, 11-dione derivatives, preparation method and application thereof | NATIONAL DEFENSE MEDICAL CENTER (TW) | 2011-11-29 | — | — | US | disclosed |
| US-20110207719-A1 | Novel Anthra [1, 2-d]imidazole-6,11-dione Derivatives, Preparation Method and application thereof | NATIONAL DEFENSE MEDICAL CENTER (TW) | 2011-08-25 | — | — | US | disclosed |
| US-20110207719-A1 | Novel Anthra [1, 2-d]imidazole-6,11-dione Derivatives, Preparation Method and application thereof | NATIONAL DEFENSE MEDICAL CENTER (TW) | 2011-08-25 | — | — | US | disclosed |
| US-20110207727-A1 | Thio-subsituted Anthra [1, 2-d] imidazole- 6, 11-dione Dervatives, Preparation Method and application thereof | NATIONAL DEFENSE MEDICAL CENTER (TW) | 2011-08-25 | — | — | US | disclosed |
| US-20110207727-A1 | Thio-subsituted Anthra [1, 2-d] imidazole- 6, 11-dione Dervatives, Preparation Method and application thereof | NATIONAL DEFENSE MEDICAL CENTER (TW) | 2011-08-25 | — | — | US | disclosed |
| US-4963451-A | USED IN ELECTROPHOTOGRAPHY, SOLAR BATTERY AND SENSORS | SHARP KABUSHIKI KAISHA (JP) | 1990-10-16 | — | — | US | disclosed |
| US-4908457-A | 1,2,4,5-benzoylenebis(anthraquinone[1,2-d]imidazole) compounds | SHARP KABUSHIKI KAISHA (JP) | 1990-03-13 | — | — | US | disclosed |
| EP-0320200-A1 | 1,2,4,5-Benzoylenebis(anthraquinone [1,2-d] imidazole) compounds and photosensitive members containing them | SHARP KABUSHIKI KAISHA (JP) | 1989-06-14 | — | — | EP | disclosed |
| EP-0008063-B1 | AZOMETHINE DERIVATIVES OF ANTHRAQUINONES, METHODS FOR THEIR PREPARATION, THEIR USE IN THE PIGMENTATION OF ORGANIC MACROMOLECULAR COMPOUNDS AND THE MATERIALS THUS OBTAINED | BAYER AG (DE) | 1982-06-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207727-A1 | Thio-subsituted Anthra [1, 2-d] imidazole- 6, 11-dione Dervatives, Preparation Method and application thereof | TERT, ACIN1, TERF2 | ALDH1A1 204/4885POLB 834/4885RXFP1 4664/4885 |
| US-20110207719-A1 | Novel Anthra [1, 2-d]imidazole-6,11-dione Derivatives, Preparation Method and application thereof | TERT, ACIN1, AK2 | ALDH1A1 267/4885POLB 1154/4885RXFP1 3997/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.