SCHEMBL712212

SCHEMBL712212

C=CCOC1O[C@H](C)[C@@H](O)[C@H](O)[C@@H]1O

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.36
▸ FUCA1 P04066 1/20 0.34
▸ AMY1A P0DUB6 1/20 0.33
▸ SYNJ2 O15056 1/20 0.32
▸ NR1H3 Q13133 1/20 0.32
▸ STAT3 P40763 1/20 0.31
▸ SELL P14151 6/20 0.31
▸ SELP P16109 6/20 0.31
▸ CA12 O43570 1/20 0.30
▸ CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26824204 1.00 L3MBTL1 (0.36) L3MBTL1FUCA1AMY1ASYNJ2NR1H3
SCHEMBL11277134 1.00 L3MBTL1 (0.36) L3MBTL1FUCA1AMY1ASYNJ2NR1H3
SCHEMBL26759947 1.00 L3MBTL1 (0.36) L3MBTL1FUCA1AMY1ASYNJ2NR1H3
SCHEMBL2046273 1.00 L3MBTL1 (0.36) L3MBTL1FUCA1AMY1ASYNJ2NR1H3
SCHEMBL5670720 1.00 L3MBTL1 (0.36) L3MBTL1FUCA1AMY1ASYNJ2NR1H3
SCHEMBL18305015 1.00 L3MBTL1 (0.36) L3MBTL1FUCA1AMY1ASYNJ2NR1H3
SCHEMBL13079298 1.00 L3MBTL1 (0.36) L3MBTL1FUCA1AMY1ASYNJ2NR1H3
SCHEMBL1119069 1.00 L3MBTL1 (0.36) L3MBTL1FUCA1AMY1ASYNJ2NR1H3
SCHEMBL18940518 1.00 L3MBTL1 (0.36) L3MBTL1FUCA1AMY1ASYNJ2NR1H3
SCHEMBL17773549 0.87 FUCA1 (0.33) FUCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240002423-A1 PROTECTED TETRASACCHARIDES, THEIR PROCESS OF PREPARATION AND THEIR USE AS TRANSGLUCOSYLASE ACCEPTOR SUBSTRATES IN THE CHEMO-ENZYMATIC SYNTHESIS OF SHIGELLA FLEXNERI SPECIFIC OLIGOSACCHARIDES PASTEUR INSTITUT (FR) 2024-01-04 — — US disclosed
US-11834468-B2 Protected tetrasaccharides, their process of preparation and their use as transglucosylase acceptor substrates in the chemo-enzymatic synthesis of Shigella flexneri specific oligosaccharides INSTITUT PASTEUR (FR) 2023-12-05 — — US disclosed
US-20200165285-A1 PROTECTED TETRASACCHARIDES, THEIR PROCESS OF PREPARATION AND THEIR USE AS TRANSGLUCOSYLASE ACCEPTOR SUBSTRATES IN THE CHEMO-ENZYMATIC SYNTHESIS OF SHIGELLA FLEXNERI SPECIFIC OLIGOSACCHARIDES INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT (FR) 2020-05-28 — — US disclosed
EP-3649141-A1 PROTECTED TETRASACCHARIDES, THEIR PROCESS OF PREPARATION AND THEIR USE AS TRANSGLUCOSYLASE ACCEPTOR SUBSTRATES IN THE CHEMO-ENZYMATIC SYNTHESIS OF SHIGELLA FLEXNERI SPECIFIC OLIGOSACCHARIDES Institut Pasteur (FR) 2020-05-13 — — EP disclosed
CN-111032671-A Protected tetrasaccharide, method for its preparation, and use thereof as a substrate for the transglucosylase receptor in the chemoenzymatic synthesis of shigella flexneri-specific oligosaccharides 巴斯德研究所 2020-04-17 — — CN disclosed
WO-2019007999-A1 PROTECTED TETRASACCHARIDES, THEIR PROCESS OF PREPARATION AND THEIR USE AS TRANSGLUCOSYLASE ACCEPTOR SUBSTRATES IN THE CHEMO-ENZYMATIC SYNTHESIS OF SHIGELLA FLEXNERI SPECIFIC OLIGOSACCHARIDES INSTITUT PASTEUR (FR) 2019-01-10 — — WO disclosed
US-9446109-B2 Glycoconjugates and their use as potential vaccines against infection by Shigella flexneri INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) 2016-09-20 — — US disclosed
US-9163049-B2 Medicament comprising a reducing alkyl-sugar monomer for the treatment of inflammatory disorders PIERRE FABRE DERMO-COSMETIQUE (FR) 2015-10-20 — — US disclosed
EP-2369345-B1 Glycoconjugates and their use as potential vaccines against infection by shigella flexneri PASTEUR INSTITUT (FR) 2014-10-01 — — EP disclosed
US-20140161793-A2 GLYCOCONJUGATES AND THEIR USE AS POTENTIAL VACCINES AGAINST INFECTION BY SHIGELLA FLEXNERI INSERM (FR) 2014-06-12 — — US disclosed
EP-2266580-A1 Medicament comprising a reducing alkyl-sugar monomer for the treatment of inflammatory disorders Pierre Fabre Dermo-Cosmétique (FR) 2010-12-29 — — EP disclosed
US-20100069311-A1 MEDICAMENT COMPRISING A REDUCING ALKYL-SUGAR MONOMER FOR THE TREATMENT OF INFLAMMATORY DISORDERS HOULMONT JEAN-PHILIPPE 2010-03-18 — — US disclosed
US-7666847-B2 Medicament comprising a reducing alkyl-sugar monomer for the treatment of inflammatory disorders PIERRE FABRE DERMO-COSMETIQUE (FR) 2010-02-23 — — US disclosed
WO-2005003775-A9 GLYCOCONJUGATES AND THEIR USE AS POTENTIAL VACCINES AGAINST INFECTION BY SHIGELLA FLEXNERI PASTEUR INSTITUT (FR) 2008-11-06 — — WO disclosed
US-20080112951-A1 Glycoconjugates and Their Use as Potential Vaccines Against Infection by Shigella Flexneri CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2008-05-15 — — US disclosed
US-20070134187-A1 Medicament comprising a reducing alkyl-sugar monomer for the treatment of inflammatory disorders CENTRE NATIONAL DE LA RECHESRCHE SCIENTIFIQUE (CNRS) (FR) 2007-06-14 — — US disclosed
EP-1682158-A1 MEDICAMENT COMPRISING A REDUCING ALKYL-SUGAR MONOMER FOR THE TREATMENT OF INFLAMMATORY DISORDERS Pierre Fabre Dermo-Cosmetique (FR) 2006-07-26 — — EP disclosed
EP-1642132-A2 GLYCOCONJUGATES AND THEIR USE AS POTENTIAL VACCINES AGAINST INFECTION BY SHIGELLA FLEXNERI INSTITUT PASTEUR (FR) 2006-04-05 — — EP disclosed
WO-2005041983-A1 MEDICAMENT COMPRISING A REDUCING ALKYL-SUGAR MONOMER FOR THE TREATMENT OF INFLAMMATORY DISORDERS PIERRE FABRE DERMO-COSMETIQUE (FR) 2005-05-12 — — WO disclosed
WO-2005003775-A2 GLYCOCONJUGATES AND THEIR USE AS POTENTIAL VACCINES AGAINST INFECTION BY SHIGELLA FLEXNERI INSTITUT PASTEUR (FR) 2005-01-13 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11834468-B2 Protected tetrasaccharides, their process of preparation and their use as transglucosylase acceptor substrates in the chemo-enzymatic synthesis of Shigella flexneri specific oligosaccharides SI, GALE, FUT5 L3MBTL1 4132/4885FUCA1 11/4885AMY1A 106/4885
US-20200165285-A1 PROTECTED TETRASACCHARIDES, THEIR PROCESS OF PREPARATION AND THEIR USE AS TRANSGLUCOSYLASE ACCEPTOR SUBSTRATES IN THE CHEMO-ENZYMATIC SYNTHESIS OF SHIGELLA FLEXNERI SPECIFIC OLIGOSACCHARIDES SI, GALE, FUT5 L3MBTL1 4132/4885FUCA1 11/4885AMY1A 106/4885
US-20140161793-A2 GLYCOCONJUGATES AND THEIR USE AS POTENTIAL VACCINES AGAINST INFECTION BY SHIGELLA FLEXNERI FUT6, GNE, STT3B L3MBTL1 2092/4885FUCA1 57/4885AMY1A 2281/4885
US-20100069311-A1 MEDICAMENT COMPRISING A REDUCING ALKYL-SUGAR MONOMER FOR THE TREATMENT OF INFLAMMATORY DISORDERS UGCG, UGGT1, TLR6 L3MBTL1 2927/4885FUCA1 80/4885AMY1A 279/4885
US-20240002423-A1 PROTECTED TETRASACCHARIDES, THEIR PROCESS OF PREPARATION AND THEIR USE AS TRANSGLUCOSYLASE ACCEPTOR SUBSTRATES IN THE CHEMO-ENZYMATIC SYNTHESIS OF SHIGELLA FLEXNERI SPECIFIC OLIGOSACCHARIDES SI, GALE, FUT5 L3MBTL1 4132/4885FUCA1 11/4885AMY1A 106/4885
US-20070134187-A1 Medicament comprising a reducing alkyl-sugar monomer for the treatment of inflammatory disorders UGCG, TLR6, CD68 L3MBTL1 4208/4885FUCA1 41/4885AMY1A 215/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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