Methacrylic Acid

Methacrylic Acid

SCHEMBL712240

C=C(C)C(=O)O.C=C(C)C(=O)O.CC(F)(F)C(F)(F)C(F)(F)C(C)(F)F

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.35
TET2 Q6N021 2/20 0.33
ALDH1A1 P00352 2/20 0.31
TSHR P16473 1/20 0.30
FFAR3 O14843 1/20 0.30
LCK P06239 1/20 0.30
FYN P06241 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL225698 1.00 TDP1 (0.35) TDP1TET2ALDH1A1TSHRFFAR3
Methacrylic Acid SCHEMBL1203768 0.95 TDP1 (0.35) TDP1TET2ALDH1A1TSHRFFAR3
Methacrylic Acid SCHEMBL226300 0.95 TDP1 (0.35) TDP1TET2ALDH1A1TSHRFFAR3
Methacrylic Acid SCHEMBL9820945 0.91 THRB (0.43) TET2
Methacrylic Acid SCHEMBL27813493 0.89 TET2 (0.32) TET2
Methacrylic Acid SCHEMBL27833419 0.89 TET2 (0.32) TET2
Methacrylic Acid SCHEMBL1789432 0.85 TET2 (0.31) TET2
Methacrylic Acid SCHEMBL1888542 0.85 TET2 (0.31) TET2
Methacrylic Acid SCHEMBL15413303 0.84 TET2 (0.32) TET2
Methacrylic Acid SCHEMBL28486167 0.84 TET2 (0.38) TDP1TET2ALDH1A1TSHRFFAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2205196-B1 HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR LIVING PROOF INC (US) 2018-12-26 EP claimed
US-20170340545-A1 HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR LIVING PROOF INC (US) 2017-11-30 US claimed
US-9770399-B2 Hair care compositions and methods of treating hair LIVING PROOF, INC. (US) 2017-09-26 US claimed
US-20130336913-A1 HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR LIVING PROOF, INC. (US) 2013-12-19 US claimed
US-7883764-B2 nanostructure moldings made from fluorinated acrylic ester homopolymers or copolymers HITACHI CHEMICAL COMPANY, LTD. (JP) 2011-02-08 US claimed
US-20100278769-A1 HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR LIVING PROOF, INC. (US) 2010-11-04 US claimed
EP-2205196-A1 HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR Living Proof, Inc. (US) 2010-07-14 EP claimed
WO-2009055489-A1 HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR LIVING PROOF, INC. (US) 2009-04-30 WO claimed
US-20090104136-A1 HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR USING SAME LIVING PROOF, INC. 2009-04-23 US claimed
US-20240407679-A1 MULTI-ANALYTE SENSING TISSUE-INTEGRATING SENSORS PROFUSA, INC. (US) 2024-12-12 US disclosed
US-20240142377-A1 DYES UNDERGOING CHANGES IN COLOR AND FLUORESCENCE UPON BINDING OF ORGANIC OXO COMPOUNDS BUNDESREPUBLIK DEUTSCHLAND, VERTRETEN DURCH DEN BUNDESMINISTER FÜR WIRTSCHAFT UND ENERGIE, DIESER VE (DE) 2024-05-02 US disclosed
US-11903702-B2 Multi-analyte sensing tissue-integrating sensors PROFUSA, INC. (US) 2024-02-20 US disclosed
US-20210128035-A1 MULTI-ANALYTE SENSING TISSUE-INTEGRATING SENSORS PROFUSA, INC. (US) 2021-05-06 US disclosed
US-10772546-B2 Multi-analyte sensing tissue-integrating sensors PROFUSA, INC. (US) 2020-09-15 US disclosed
US-20080167396-A1 Fine Resinous Structure, Fabrication Thereof, and Polymerizable Resin-Precursor Composition HITACHI CHEMICAL CO., LTD. (JP) 2008-07-10 US disclosed
US-20080066773-A1 IN SITU POLYMERIZATION FOR HAIR TREATMENT LIVING PROOF, INC. 2008-03-20 US disclosed
WO-2007127065-A2 IN SITU POLYMERIZATION FOR HAIR TREATMENT LIVING PROOF, INC. (US) 2007-11-08 WO disclosed
US-7098282-B2 Fluorosulfone-silicone hydrogel, RGP contact lenses, optical medical devices and compositions thereof NOVICKY NICK 2006-08-29 US disclosed
US-20050176907-A1 Fluorosulfone-silicone hydrogel, RGP contact lenses, optical medical devices and compositions thereof NOVICKY NICK (CA) 2005-08-11 US disclosed
EP-1455201-A1 Fluorosulfone-silicone hydrogel RGP contact lenses, optical medical devices and compositions thereof Novicky, Nick N. (CA) 2004-09-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080066773-A1 IN SITU POLYMERIZATION FOR HAIR TREATMENT PPOX, SUCLG1, GFER TDP1 2555/4885TET2 54/4885ALDH1A1 634/4885
US-20240407679-A1 MULTI-ANALYTE SENSING TISSUE-INTEGRATING SENSORS NCS1, LGALS8, TNNI3 TDP1 515/4885TET2 1030/4885ALDH1A1 193/4885
US-20100278769-A1 HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR FLNA, FLNB, FGF1 TDP1 1398/4885TET2 94/4885ALDH1A1 1490/4885
US-20170340545-A1 HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR FLNA, FLNB, FGF1 TDP1 1398/4885TET2 94/4885ALDH1A1 1490/4885
US-11903702-B2 Multi-analyte sensing tissue-integrating sensors NCS1, LGALS8, TNNI3 TDP1 515/4885TET2 1030/4885ALDH1A1 193/4885
US-20130336913-A1 HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR FLNA, FLNB, FGF1 TDP1 1398/4885TET2 94/4885ALDH1A1 1490/4885
US-20090104136-A1 HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR USING SAME TET1, TET2, TET3 TDP1 1217/4885TET2 2/4885ALDH1A1 457/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.