Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7950676 | 0.70 | — | — | |
| SCHEMBL7122826 | 0.69 | — | — | |
| SCHEMBL28979166 | 0.68 | TSHR (0.39) | ALDH1A1 | |
| SCHEMBL28489822 | 0.67 | ALDH1A1 (0.45) | ALDH1A1 | |
| SCHEMBL13450354 | 0.65 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL7074997 | 0.65 | — | — | |
| SCHEMBL8334187 | 0.65 | — | — | |
| SCHEMBL1563009 | 0.65 | — | — | |
| SCHEMBL8362402 | 0.64 | TAS1R3 (0.32) | ALDH1A1 | |
| SCHEMBL10811153 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9994595-B2 | Catalyst and battery components derived from condensation reactions with carba-closo-dodecaborate amines | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-06-12 | — | — | US | disclosed |
| US-20170084954-A1 | CATALYST AND BATTERY COMPONENTS DERIVED FROM CONDENSATION REACTIONS WITH CARBA-CLOSO-DODECABORATE AMINES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-03-23 | — | — | US | disclosed |
| WO-2015139060-A1 | CATALYST AND BATTERY COMPONENTS DERIVED FROM CONDENSATION REACTIONS WITH CARBA-CLOSO-DODECABORATE AMINES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-09-17 | — | — | WO | disclosed |
| US-8558017-B2 | Ruthenium (II) catalysts for use in stereoselective cyclopropanations | VANDA PHARMACEUTICALS, INC. (US) | 2013-10-15 | — | — | US | disclosed |
| US-20130023662-A9 | RUTHENIUM (II) CATALYSTS FOR USE IN STEREOSELECTIVE CYCLOPROPANATIONS | VANDA PHARMECEUTICALS INC. (US) | 2013-01-24 | — | — | US | disclosed |
| US-20120149906-A1 | RUTHENIUM (II) CATALYSTS FOR USE IN STEREOSELECTIVE CYCLOPROPANATIONS | VANDA PHARMECEUTICALS INC. (US) | 2012-06-14 | — | — | US | disclosed |
| US-8110699-B2 | Cobalt-catalyzed asymmetric cyclopropanation of alkenes with α-nitrodiazoacetates | UNIVERSITY OF SOUTH FLORIDA (US) | 2012-02-07 | — | — | US | disclosed |
| US-8097738-B2 | Ruthenium (II) catalysts for use in stereoselective cyclopropanations | VANDA PHARMACEUTICALS INC. (US) | 2012-01-17 | — | — | US | disclosed |
| US-7847041-B2 | Cobalt-catalyzed asymmetric cyclopropanation of electron-deficient olefins | UNIVERSITY OF SOUTH FLORIDA (US) | 2010-12-07 | — | — | US | disclosed |
| US-20100228039-A1 | RUTHENIUM (II) CATALYSTS FOR USE IN STEREOSELECTIVE CYCLOPROPANATIONS | VANDA PHARMECEUTICALS INC. (US) | 2010-09-09 | — | — | US | disclosed |
| US-7754902-B2 | Ruthenium(II) catalysts for use in stereoselective cyclopropanations | VANDA PHARMACEUTICALS, INC. (US) | 2010-07-13 | — | — | US | disclosed |
| US-20100081838-A1 | Cobalt-Catalyzed Asymmetric Cyclopropanation of Alkenes with alpha-Nitrodiazoacetates | UNIVERSITY OF SOUTH FLORIDA (US) | 2010-04-01 | — | — | US | disclosed |
| US-20100076239-A1 | ASYMMETRIC CYCLOPROPANATION OF ELECTRON-DEFICIENT OLEFINS WITH DIAZO REAGENTS | UNIVERSITY OF SOUTH FLORIDA (US) | 2010-03-25 | — | — | US | disclosed |
| US-20090069519-A1 | COBALT-CATALYZED ASYMMETRIC CYCLOPROPANATION OF ELECTRON-DEFICIENT OLEFINS | NATIONAL SCIENCE FOUNDATION | 2009-03-12 | — | — | US | disclosed |
| US-20070270593-A1 | Ruthenium(II) catalysts for use in stereoselective cyclopropanations | R.P. SCHERER TECHNOLOGIES, INC. | 2007-11-22 | — | — | US | disclosed |
| EP-0594608-B1 | CHIRAL CATALYSTS FOR ENANTIOSELECTIVE SYNTHESIS | RES CORP TECHNOLOGIES INC (US) | 1997-10-15 | — | — | EP | disclosed |
| US-5175311-A | Reacting olefin with carbene precursor | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1992-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149906-A1 | RUTHENIUM (II) CATALYSTS FOR USE IN STEREOSELECTIVE CYCLOPROPANATIONS | RUVBL2, SPR, RUVBL1 | ALDH1A1 2164/4885 |
| US-20170084954-A1 | CATALYST AND BATTERY COMPONENTS DERIVED FROM CONDENSATION REACTIONS WITH CARBA-CLOSO-DODECABORATE AMINES | NUDC, NCAPH, C2CD5 | ALDH1A1 4533/4885 |
| US-20100076239-A1 | ASYMMETRIC CYCLOPROPANATION OF ELECTRON-DEFICIENT OLEFINS WITH DIAZO REAGENTS | DUOX2, DUOX1, PPOX | ALDH1A1 1047/4885 |
| US-20130023662-A9 | RUTHENIUM (II) CATALYSTS FOR USE IN STEREOSELECTIVE CYCLOPROPANATIONS | RUVBL2, SPR, RUVBL1 | ALDH1A1 2164/4885 |
| US-20100081838-A1 | Cobalt-Catalyzed Asymmetric Cyclopropanation of Alkenes with alpha-Nitrodiazoacetates | PPOX, IDH3A, HMOX2 | ALDH1A1 665/4885 |
| US-20100228039-A1 | RUTHENIUM (II) CATALYSTS FOR USE IN STEREOSELECTIVE CYCLOPROPANATIONS | RUVBL2, SPR, RUVBL1 | ALDH1A1 2164/4885 |
| US-20070270593-A1 | Ruthenium(II) catalysts for use in stereoselective cyclopropanations | RUVBL2, SPR, RUVBL1 | ALDH1A1 2164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.