SCHEMBL7124035

SCHEMBL7124035

O=S(=O)(Cl)c1ccc(Cl)c(S(=O)(=O)Cl)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.47
KDM4E B2RXH2 1/20 0.47
LMNA P02545 3/20 0.42
SLC12A2 P55011 1/20 0.42
SLC12A5 Q9H2X9 1/20 0.42
TRPV4 Q9HBA0 2/20 0.41
ALDH1A1 P00352 4/20 0.41
TDP1 Q9NUW8 2/20 0.41
HSD17B10 Q99714 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.39
GLA P06280 1/20 0.38
VCAM1 P19320 2/20 0.38
CA12 O43570 2/20 0.36
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
CA4 P22748 2/20 0.36
CA6 P23280 2/20 0.36
CA5A P35218 2/20 0.36
CA7 P43166 2/20 0.36
CA9 Q16790 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10363279 0.85 LMNA (0.53) POLBKDM4ELMNAALDH1A1SMN1; SMN2
SCHEMBL2980221 0.85 CA1 (0.50) POLBKDM4ELMNATDP1VCAM1
SCHEMBL17478768 0.85 CA2 (0.55) POLBKDM4ELMNATDP1VCAM1
SCHEMBL11427098 0.82 TRPV4 (0.55) POLBKDM4ELMNATRPV4ALDH1A1
SCHEMBL29057554 0.81 ALDH1A1 (0.44) POLBKDM4ELMNATRPV4ALDH1A1
SCHEMBL18316 0.81 APEX1 (0.50) LMNAALDH1A1TDP1HSD17B10CA12
SCHEMBL25087913 0.81 MEN1 (0.44) POLBKDM4ELMNASLC12A2SLC12A5
SCHEMBL23043570 0.81 VCAM1 (0.57) LMNAALDH1A1SMN1; SMN2VCAM1MCL1
SCHEMBL4616207 0.81 HTR6 (0.50) POLBKDM4ELMNASLC12A2SLC12A5
SCHEMBL198172 0.79 MCL1 (0.55) KDM4ELMNATRPV4ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0104721-B1 PROCESS FOR THE PREPARATION OF 2-CHLOROSULFONYL-4-(N-SUBSTITUTED SULFAMYL)-CHLOROBENZENE COMPOUNDS FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) 1986-12-30 EP claimed
EP-0104721-A1 Process for the preparation of 2-chlorosulfonyl-4-(N-substituted sulfamyl)-chlorobenzene compounds FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) 1984-04-04 EP claimed
JP-59039867-A None JP disclosed
JP-11279141-A None JP disclosed
WO-2020218003-A1 N,N'-DIARYLUREA DERIVATIVE AND THERMOSENSITIVE RECORDING MATERIAL USING SAME 三光株式会社 2020-10-29 WO disclosed
US-6670474-B2 Such as bis-1,2-(2-(2,3-epoxypropyl)phenoxy)ethane; chemical intermediates for formation of epoxy resins PEWS R GARTH (US) 2003-12-30 US disclosed
US-20020151731-A1 Novel epoxide derivatives of allylarylphenols PEWS R GARTH (US) 2002-10-17 US disclosed
US-4945169-A Novel bis-maleimide compounds containing sulfonate linkages INDSPEC CHEMICAL CORPORATION (US) 1990-07-31 US disclosed
EP-0104721-B1 PROCESS FOR THE PREPARATION OF 2-CHLOROSULFONYL-4-(N-SUBSTITUTED SULFAMYL)-CHLOROBENZENE COMPOUNDS FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) 1986-12-30 EP disclosed
EP-0104721-A1 Process for the preparation of 2-chlorosulfonyl-4-(N-substituted sulfamyl)-chlorobenzene compounds FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) 1984-04-04 EP disclosed
EP-0104721-A1 Process for the preparation of 2-chlorosulfonyl-4-(N-substituted sulfamyl)-chlorobenzene compounds FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) 1984-04-04 EP disclosed
US-4438245-A FOR LIGHT SENSITIVE ELEMENTS FUJI PHOTO FILM CO., LTD. (JP) 1984-03-20 US disclosed
JP-S5939867-A PREPARATION OF 2-CHLOROSULFONYL-4-N-SUBSTITUTED SULFAMYL-CHLOROBENZENE FUJI YAKUHIN KOGYO KK 1984-03-05 JP disclosed
US-4379819-A OIL SOLUBLE MONOAZO DYE CIBA-GEIGY AG (CH) 1983-04-12 US disclosed
US-4055565-A Optical brightening agents of naphthalimide derivatives SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-10-25 US disclosed
US-3983300-A POLYAROMATIC SULFONE IMPERIAL CHEMICAL INDUSTRIES LIMITED (EN) 1976-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020151731-A1 Novel epoxide derivatives of allylarylphenols EPHX2, CBR3, CYP4X1 POLB 2231/4885KDM4E 200/4885LMNA 3988/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.