SCHEMBL712976

SCHEMBL712976

C/C=C/CC1(CC)C(=O)NC(=O)NC1=O

nearest known ligand 0.73

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.61
ALDH1A1 P00352 4/20 0.40
TP53 P04637 1/20 0.36
KDM4E B2RXH2 1/20 0.35
CYP3A4 P08684 1/20 0.35
GABRB3 P28472 1/20 0.35
OPRD1 P41143 1/20 0.35
GABRA2 P47869 1/20 0.35
GABRB2 P47870 1/20 0.35
HSD17B10 Q99714 1/20 0.35
MMP9 P14780 4/20 0.34
MMP2 P08253 3/20 0.33
MMP8 P22894 2/20 0.33
MMP13 P45452 2/20 0.33
MMP3 P08254 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2285746 1.00 LMNA (0.61) LMNAALDH1A1TP53KDM4ECYP3A4
SCHEMBL2048014 0.81 MMP9 (0.42) LMNATP53MMP9
SCHEMBL2048015 0.81 MMP9 (0.42) LMNATP53MMP9
Barbital SCHEMBL3859278 0.78 LMNA (1.00) LMNAALDH1A1TP53KDM4ECYP3A4
Barbital SCHEMBL43818 0.78 LMNA (1.00) LMNAALDH1A1TP53KDM4ECYP3A4
Etallobarbital SCHEMBL713588 0.78 LMNA (0.64) LMNAALDH1A1TP53KDM4ECYP3A4
Barbital SCHEMBL23533431 0.75 LMNA (0.94) LMNAALDH1A1TP53KDM4ECYP3A4
Barbital SCHEMBL11332231 0.75 LMNA (0.94) LMNAALDH1A1TP53KDM4ECYP3A4
Barbital SCHEMBL7592317 0.75 LMNA (0.94) LMNAALDH1A1TP53KDM4ECYP3A4
Barbital SCHEMBL21084955 0.75 LMNA (0.94) LMNAALDH1A1TP53KDM4ECYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 339 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12600926-B2 Treatment compositions with modified amino acid dimers for delivering a benefit agent THE PROCTER & GAMBLE COMPANY (US) 2026-04-14 US claimed
US-20260000592-A1 TREATMENT COMPOSITIONS WITH ESTERAMINES OR SALTS THEREOF PROCTER & GAMBLE (US) 2026-01-01 US claimed
US-12509643-B2 Pro-benefit-agent compounds with carbon/nitrogen bonds THE PROCTER & GAMBLE COMPANY (US) 2025-12-30 US claimed
EP-3784707-B1 STABLE POLYUREA MICROCAPSULE COMPOSITIONS INT FLAVORS & FRAGRANCES INC (US) 2025-12-24 EP claimed
EP-4114914-B1 FRAGRANCE PREMIX COMPOSITIONS AND RELATED CONSUMER PRODUCTS PROCTER & GAMBLE (US) 2025-06-25 EP claimed
US-20250129312-A1 CONSUMER PRODUCT COMPOSITIONS WITH PERFUME ENCAPSULATES PROCTER & GAMBLE (US) 2025-04-24 US claimed
WO-2025051371-A1 A FRAGRANCE PASTILLE SYMRISE AG (DE) 2025-03-13 WO claimed
WO-2025045354-A1 A FRAGRANCE TABLET SYMRISE AG (DE) 2025-03-06 WO claimed
WO-2025045353-A1 A FRAGRANCE POD SYMRISE AG (DE) 2025-03-06 WO claimed
US-12209232-B2 Consumer product compositions with perfume encapsulates THE PROCTER & GAMBLE COMPANY (US) 2025-01-28 US claimed
US-6982288-B2 Dental cements, filling materials, adhesives 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-01-03 US claimed
JP-2005524682-A 2005-08-18 JP claimed
EP-1496837-A1 MEDICAL COMPOSITIONS CONTAINING AN IONIC SALT 3M Innovative Properties Company (US) 2005-01-19 EP claimed
EP-1458831-A2 COMPOSITION CONTAINING A POLYMERIZABLE REDUCING AGENT, KIT, AND METHOD 3M Innovative Properties Company (US) 2004-09-22 EP claimed
WO-2003086328-A1 MEDICAL COMPOSITIONS CONTAINING AN IONIC SALT 3M INNOVATIVE PROPERTIES COMPANY (US) 2003-10-23 WO claimed
US-20030195273-A1 Medical compositions containing an ionic salt, kits, and methods 3M INNOVATIVE PROPERTIES COMPANY 2003-10-16 US claimed
US-20030166740-A1 Composition containing a polymerizable reducing agent, kit, and method 3M INNOVATIVE PROPERTIES COMPANY 2003-09-04 US claimed
WO-2003057792-A2 COMPOSITION CONTAINING A POLYMERIZABLE REDUCING AGENT, KIT, AND METHOD 3M INNOVATIVE PROPERTIES COMPANY (US) 2003-07-17 WO claimed
EP-1067942-A1 HIGH-ENERGY CYCLODEXTRIN COMPLEXES Cyclops, EHF. (IS) 2001-01-17 EP claimed
WO-1999042111-A1 HIGH-ENERGY CYCLODEXTRIN COMPLEXES CYCLOPS, EHF. (IS) 1999-08-26 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12509643-B2 Pro-benefit-agent compounds with carbon/nitrogen bonds HGFAC, PROKR1, FABP2 LMNA 5/4885ALDH1A1 544/4885TP53 1914/4885
US-20260000592-A1 TREATMENT COMPOSITIONS WITH ESTERAMINES OR SALTS THEREOF ARGLU1, DAO, PNISR LMNA 3119/4885ALDH1A1 4253/4885TP53 1004/4885
US-12600926-B2 Treatment compositions with modified amino acid dimers for delivering a benefit agent F2, C9, S100A8 LMNA 185/4885ALDH1A1 2233/4885TP53 1043/4885
US-20030195273-A1 Medical compositions containing an ionic salt, kits, and methods NOX4, SCN4A, IL4 LMNA 2934/4885ALDH1A1 1883/4885TP53 4017/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.