SCHEMBL7136137

SCHEMBL7136137

C=Cc1ccc(O[Si](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.48
TSHR P16473 1/20 0.48
TRPA1 O75762 1/20 0.34
CHRNB2 P17787 1/20 0.34
CHRNB4 P30926 1/20 0.34
CHRNA3 P32297 1/20 0.34
CHRNA7 P36544 1/20 0.34
CHRNA4 P43681 1/20 0.34
RELA Q04206 1/20 0.32
POLB P06746 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
ICAM1 P05362 1/20 0.30
SELE P16581 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7133959 0.81 ALDH1A1 (0.45) ALDH1A1TSHRTRPA1CHRNB2CHRNB4
SCHEMBL7134965 0.81 ALDH1A1 (0.45) ALDH1A1TSHRTRPA1CHRNB2CHRNB4
SCHEMBL7133950 0.80 ALDH1A1 (0.43) ALDH1A1TSHRRELAPOLBTDP1
SCHEMBL705575 0.79 LTA4H (0.43) ALDH1A1TSHRTDP1CA1CA2
SCHEMBL25414124 0.78 ALDH1A1 (0.41) ALDH1A1TSHRTRPA1CHRNB2CHRNB4
SCHEMBL1867153 0.77 ALDH1A1 (0.48) ALDH1A1TSHRTRPA1CHRNB2CHRNB4
SCHEMBL706535 0.77 LTA4H (0.41) ALDH1A1TSHRCA1CA2
SCHEMBL3871938 0.74 LMNA (0.42) ALDH1A1TSHRRELAPOLBTDP1
SCHEMBL198042 0.74 TSHR (0.42) TSHRTDP1
SCHEMBL28444685 0.74 MAOA (0.52) ALDH1A1TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6506537-B2 Photopolymerization JSR CORPORATION (JP) 2003-01-14 US disclosed
US-20020012872-A1 Radiation-sensitive resin composition JSR CORPORATION (JP) 2002-01-31 US disclosed
EP-1164433-A1 Radiation-sensitive resin composition JSR Corporation (JP) 2001-12-19 EP disclosed