SCHEMBL705575

SCHEMBL705575

c1ccc(O[Si](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.43
TSHR P16473 1/20 0.43
CA4 P22748 1/20 0.39
KCNA3 P22001 1/20 0.36
CA5A P35218 1/20 0.35
CA5B Q9Y2D0 1/20 0.35
KCNH2 Q12809 1/20 0.33
NR1H2 P55055 1/20 0.33
BAX Q07812 1/20 0.33
KDM4E B2RXH2 1/20 0.33
GLA P06280 1/20 0.33
MAPT P10636 1/20 0.33
KMT2A Q03164 1/20 0.33
MAOA P21397 1/20 0.33
TAAR1 Q96RJ0 1/20 0.32
ALDH1A1 P00352 1/20 0.32
RECQL P46063 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL706535 0.97 LTA4H (0.41) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL28444685 0.84 MAOA (0.52) TSHRKDM4EMAPTKMT2AMAOA
SCHEMBL198042 0.84 TSHR (0.42) TSHRKDM4EGLAKMT2AMAOA
SCHEMBL3869832 0.84 ACHE (0.42) LTA4HTSHRCA4KMT2AALDH1A1
SCHEMBL3871938 0.84 LMNA (0.42) TSHRMAPTKMT2AALDH1A1TDP1
SCHEMBL978832 0.80 LTA4H (0.45) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL7695708 0.79 LTA4H (0.35) LTA4HTSHRCA4KCNA3KDM4E
SCHEMBL7136137 0.79 ALDH1A1 (0.48) TSHRALDH1A1CA1CA2TDP1
SCHEMBL974837 0.78 LTA4H (0.43) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL431218 0.78 LTA4H (0.43) LTA4HTSHRCA4KCNA3CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11059920-B2 Process for producing high cis-1,4-polydiene with lanthanide-based catalyst compositions BRIDGESTONE CORPORATION (JP) 2021-07-13 US claimed
US-20190169330-A1 Process For Producing High Cis-1,4-Polydiene With Lanthanide-Based Catalyst Compositions BRIDGESTONE CORPORATION (JP) 2019-06-06 US claimed
EP-3491030-A1 PROCESS FOR PRODUCING HIGH CIS-1,4-POLYDIENE WITH LANTHANIDE-BASED CATALYST COMPOSITIONS Bridgestone Corporation (JP) 2019-06-05 EP claimed
WO-2018022994-A1 PROCESS FOR PRODUCING HIGH CIS-1,4-POLYDIENE WITH LANTHANIDE-BASED CATALYST COMPOSITIONS BRIDGESTONE CORPORATION (JP) 2018-02-01 WO claimed
US-7499618-B2 Optical element KONICA MINOLTA OPTO, INC. (JP) 2009-03-03 US claimed
US-7129311-B2 Additives to prevent degradation of alkyl-hydrogen siloxanes ARCH SPECIALTY CHEMICALS, INC. (US) 2006-10-31 US claimed
US-20060159861-A1 Additives to prevent degradation of alkyl-hydrogen siloxanes ARCH SPECIALTY CHEMICALS, INC. (US) 2006-07-20 US claimed
EP-1635194-A1 OPTICAL ELEMENT Konica Minolta Opto, Inc. (JP) 2006-03-15 EP claimed
EP-1573086-A2 ADDITIVES TO PREVENT DEGRADATION OF ALKYL-HYDROGEN SILOXANES Arch Specialty Chemicals, Inc. (US) 2005-09-14 EP claimed
US-20050078926-A1 Unknown KONICA MINOLTA OPTO, INC. (JP) 2005-04-14 US claimed
US-20040127070-A1 Additives to prevent degradation of alkyl-hydrogen siloxanes ARCH SPECIALTY CHEMICALS, INC. 2004-07-01 US claimed
WO-2004027110-A2 ADDITIVES TO PREVENT DEGRADATION OF ALKYL-HYDROGEN SILOXANES ARCH SPECIALTY CHEMICALS, INC. (US) 2004-04-01 WO claimed
EP-4466300-A1 A THERMOSET COMPOSITE COMPRISING A CROSSLINKED IMIDE EXTENDED COMPOUND Rogers Corporation (US) 2024-11-27 EP disclosed
CN-118574871-A Thermoset composite materials comprising crosslinked imide extension compounds 罗杰斯公司 2024-08-30 CN disclosed
US-20230242709-A1 THERMOSET COMPOSITE COMPRISING A CROSSLINKED IMIDE EXTENDED COMPOUND ROGERS CORPORATION 2023-08-03 US disclosed
WO-2023141035-A1 A THERMOSET COMPOSITE COMPRISING A CROSSLINKED IMIDE EXTENDED COMPOUND ROGERS CORPORATION (US) 2023-07-27 WO disclosed
EP-0479107-A2 Silane esters modified polycarbonates GENERAL ELECTRIC COMPANY (US) 1992-04-08 EP disclosed
EP-0479108-A2 Endcapped, chain-extended or branched polyesters GENERAL ELECTRIC COMPANY (US) 1992-04-08 EP disclosed
US-5089598-A With silane esters GENERAL ELECTRIC COMPANY (US) 1992-02-18 US disclosed
EP-0193643-A2 Curable resin composition KABUSHIKI KAISHA TOSHIBA (JP) 1986-09-10 EP disclosed