SCHEMBL7141602

SCHEMBL7141602

O=Cc1cccc(CC(F)(F)F)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 7/20 0.45
MAOB P27338 7/20 0.45
ALDH1A1 P00352 4/20 0.44
UNG P13051 1/20 0.40
CYP2A6 P11509 1/20 0.38
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
POLB P06746 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
SRC P12931 1/20 0.36
TRIM24 O15164 1/20 0.35
TRIM33 Q9UPN9 1/20 0.35
FFAR1 O14842 1/20 0.35
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
ELANE P08246 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3645563 0.82 MAOA (0.46) MAOAMAOBALDH1A1UNGCYP2A6
SCHEMBL5399848 0.81 HTR2A (0.33)
SCHEMBL13437611 0.78 ATM (0.34) POLB
SCHEMBL2636655 0.78 MAOA (0.42) MAOAMAOBALDH1A1UNGCYP2A6
SCHEMBL25949907 0.78 SLC6A2 (0.52) MAOAMAOBALDH1A1UNGCYP2A6
SCHEMBL3151486 0.78 MAOA (0.49) MAOAMAOBALDH1A1UNGCYP2A6
SCHEMBL6852425 0.77 ALDH1A1 (0.52) MAOAMAOBALDH1A1UNGCYP2A6
SCHEMBL13509648 0.77 MAOA (0.41) MAOAMAOBALDH1A1UNGCYP2A6
Formamide SCHEMBL6016424 0.76 AGXT (0.45) MAOB
SCHEMBL9079801 0.75 MAOA (0.50) MAOAMAOBALDH1A1UNGCYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9955689-B2 Method for promoting plant growth SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-01 US disclosed
US-9872493-B2 Method for promoting plant growth SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-01-23 US disclosed
US-20150305332-A1 METHOD FOR PROMOTING PLANT GROWTH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-29 US disclosed
US-20150289506-A1 METHOD FOR PROMOTING PLANT GROWTH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-15 US disclosed
US-20150289512-A1 METHOD FOR PROMOTING PLANT GROWTH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-15 US disclosed
EP-2926660-A1 METHOD FOR PROMOTING PLANT GROWTH Sumitomo Chemical Company Limited (JP) 2015-10-07 EP disclosed
EP-2923574-A1 METHOD FOR PROMOTING PLANT GROWTH Sumitomo Chemical Company Limited (JP) 2015-09-30 EP disclosed
EP-2923573-A1 METHOD FOR PROMOTING PLANT GROWTH Sumitomo Chemical Company Limited (JP) 2015-09-30 EP disclosed
US-6512030-B2 Plastic additives which are useful as nucleating agents and which are especially useful for improving the optical properties of polymeric materials such as polyolefins; also as gelling agents for antiperspirant gels MILLIKEN & COMPANY 2003-01-28 US disclosed
US-20020193473-A1 Novel asymmetric monofluorinated benzaldehyde alditol derivatives and compositions and articles containing same MILLIKEN & COMPANY 2002-12-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150289506-A1 METHOD FOR PROMOTING PLANT GROWTH FGF2, BROX, BOLA2; BOLA2B MAOA 2460/4885MAOB 1170/4885ALDH1A1 775/4885
US-20150305332-A1 METHOD FOR PROMOTING PLANT GROWTH FGF1, BROX, FGF2 MAOA 1602/4885MAOB 723/4885ALDH1A1 1702/4885
US-20020193473-A1 Novel asymmetric monofluorinated benzaldehyde alditol derivatives and compositions and articles containing same DERA, ALDOA, SORD MAOA 876/4885MAOB 673/4885ALDH1A1 132/4885
US-20150289512-A1 METHOD FOR PROMOTING PLANT GROWTH FGF1, MKI67, FGF2 MAOA 95/4885MAOB 204/4885ALDH1A1 653/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.