Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.32 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | CD69 | Q07108 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL214797 | 0.74 | NOTUM (0.40) | NOTUMALDH1A1GAAMAPTHPGD | |
| SCHEMBL6656862 | 0.73 | AKR1B1 (0.39) | NOTUMALDH1A1GAAHPGDHSD17B3 | |
| SCHEMBL29163012 | 0.71 | KEAP1 (0.42) | ALDH1A1MAPT | |
| SCHEMBL1067728 | 0.70 | MAOA (0.50) | GPR84CD69 | |
| SCHEMBL4620052 | 0.67 | HTT (0.34) | GAAMAPTHSD17B3 | |
| SCHEMBL7150887 | 0.67 | ALOX5 (0.48) | ALDH1A1GAAMAPTHPGD | |
| SCHEMBL10053990 | 0.65 | ALDH1A1 (0.34) | ALDH1A1MAPTHPGDHSD17B3GPR84 | |
| SCHEMBL7250245 | 0.64 | HPGD (0.38) | NOTUMALDH1A1GAAPLA2G1BMAPT | |
| Hydrochloric Acid SCHEMBL8826087 | 0.63 | ALDH1A1 (0.33) | ALDH1A1GAAGPR84 | |
| SCHEMBL23733167 | 0.62 | SMN1; SMN2 (0.37) | ALDH1A1GAAMAPTHPGDBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0977748-B1 | SUBSTITUTED BENZOPYRAN DERIVATIVES FOR THE TREATMENT OF INFLAMMATION | SEARLE & CO (US) | 2003-03-26 | — | — | EP | claimed |