Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | YTHDC1 | Q96MU7 | 2/20 | 0.38 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 5/20 | 0.36 |
| ▸ | PGR | P06401 | 3/20 | 0.36 |
| ▸ | AR | P10275 | 3/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7097451 | 0.89 | PSIP1 (0.38) | PTGS1BRAFPDE10A | |
| SCHEMBL5239494 | 0.86 | KEAP1 (0.47) | ALDH1A1GLO1ALOX15HTTJAK2 | |
| SCHEMBL7248382 | 0.75 | NR3C1 (0.41) | ALDH1A1HTTNR3C1PDE10A | |
| SCHEMBL7103692 | 0.74 | PSIP1 (0.38) | ALDH1A1HTTNR3C1PDE10A | |
| SCHEMBL7100998 | 0.74 | PSIP1 (0.38) | ALDH1A1HTTPDE10A | |
| SCHEMBL7101637 | 0.73 | NR3C1 (0.39) | KEAP1NFE2L2PTGS1NR3C1PDE10A | |
| SCHEMBL7104778 | 0.72 | PDE10A (0.42) | ALDH1A1HTTNR3C1PDE10AHSD17B10 | |
| SCHEMBL7103193 | 0.72 | PARP1 (0.48) | ALDH1A1ALOX15NR3C1HSD17B10 | |
| SCHEMBL7103402 | 0.72 | MRGPRX1 (0.34) | HTTJAK2JAK1PTGS1BRAF | |
| SCHEMBL5200810 | 0.72 | TAAR1 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030073850-A1 | 4-Imidazole derivatives of benzyl and restricted benzyl sulfonamides, sulfamides, ureas, carbamates, and amides and their use | ABBOTT LABORATORIES | 2003-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030073850-A1 | 4-Imidazole derivatives of benzyl and restricted benzyl sulfonamides, sulfamides, ureas, carbamates, and amides and their use | ADRA1D, ADRB1, ADRA1A | ALDH1A1 263/4885KDM4E 823/4885RCE1 3666/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.