SCHEMBL715112

SCHEMBL715112

Cc1[c]c2c(cc1)-c1ccc(C)cc1C2

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP1 P53582 3/20 0.43
MAPT P10636 3/20 0.38
KDM4E B2RXH2 2/20 0.38
ALDH1A1 P00352 2/20 0.38
RAB9A P51151 2/20 0.38
POLB P06746 1/20 0.38
GAA P10253 1/20 0.38
PKM P14618 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
PARP10 Q53GL7 2/20 0.35
PARP11 Q9NR21 1/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
HPGD P15428 1/20 0.34
HTT P42858 1/20 0.34
ATM Q13315 1/20 0.34
ACHE P22303 1/20 0.33
PARP1 P09874 1/20 0.32
NPC1 O15118 1/20 0.32
ESR1 P03372 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4338324 0.80 ALDH1A1 (0.34) MAPTKDM4EALDH1A1RAB9APOLB
SCHEMBL216980 0.79 ALDH1A1 (0.40) MAPTKDM4EALDH1A1RAB9AGAA
SCHEMBL29633547 0.77 METAP1 (0.57) METAP1MAPTKDM4EALDH1A1RAB9A
SCHEMBL4897556 0.77 METAP1 (0.57) METAP1MAPTKDM4EALDH1A1RAB9A
SCHEMBL29332473 0.73 METAP1 (0.53) METAP1MAPTKDM4EALDH1A1RAB9A
SCHEMBL2051092 0.71 ESR1 (0.36) METAP1ESR1ESR2
SCHEMBL21694418 0.71 METAP1 (0.52) METAP1MAPTKDM4EALDH1A1RAB9A
SCHEMBL18568790 0.70 METAP1 (0.50) METAP1MAPTKDM4EALDH1A1RAB9A
SCHEMBL2047309 0.68 PARP10 (0.44) MAPTKDM4EALDH1A1RAB9APOLB
SCHEMBL1609497 0.68 ALDH1A1 (0.59) METAP1MAPTKDM4EALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 212 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5627247-A COMPOUNDS OF CYCLOPENTADIENE OR INDENE WITH FLUORENE AND GROUP IV METALS PHILLIPS PETROLEUM COMPANY (US) 1997-05-06 US claimed
CN-118202023-A Polypropylene viscosity modifier and lubricating oil thereof 埃克森美孚化学专利公司 2024-06-14 CN disclosed
US-11926802-B2 Lubricating oil composition with viscosity modifier based on syndiotactic propylene-based ethylene- propylene copolymers with improved properties EXXONMOBIL CHEMICAL PATENTS INC. (US) 2024-03-12 US disclosed
EP-3587457-B1 METHOD OF TRANSFERRING SLURRY AND METHOD OF PRODUCING POLYOLEFIN SUMITOMO CHEMICAL CO (JP) 2023-09-27 EP disclosed
US-11766669-B2 Hexahydrocyclopenta[e]-as-indacen-1-yl and octahydrobenzo[e]-as-indacen-1-yl based catalyst complexes and process for use thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-09-26 US disclosed
US-20230242745-A1 Process for Production of Thermoplastic Vulcanizates using Supported Catalyst Systems and Compositions Made Therefrom EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-08-03 US disclosed
US-20230174883-A1 LUBRICATING OIL COMPOSITION WITH VISCOSITY MODIFIER BASED ON SYNDIOTACTIC PROPYLENE-BASED ETHYLENE- PROPYLENE COPOLYMERS WITH IMPROVED PROPERTIES EXXONMOBIL CHEMICAL PATENTS INC. 2023-06-08 US disclosed
WO-2023081327-A1 LUBRICATING OIL COMPOSITION WITH VISCOSITY MODIFIER BASED ON SYNDIOTACTIC PROPYLENE-BASED ETHYLENE-PROPYLENE COPOLYMERS WITH IMPROVED PROPERTIES CHEVRON ORONITE COMPANY LLC (US) 2023-05-11 WO disclosed
WO-2023081325-A1 SYNDIOTACTIC PROPYLENE-BASED ETHYLENE-PROPYLENE COPOLYMERS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-05-11 WO disclosed
US-20230148328-A1 SYNDIOTACTIC PROPYLENE-BASED ETHYLENE- PROPYLENE COPOLYMERS EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-05-11 US disclosed
EP-0985673-A2 Modified aluminium oxy compound, polymerization catalyst and process for producing olefin polymer and alkenyl aromatic hydrocarbon polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-03-15 EP disclosed
US-5906955-A Catalyst for polymerization of an olefin, and method for producing an olefin polymer TOSOH CORPORATION (JP) 1999-05-25 US disclosed
EP-0628577-B1 Silyl bridged metallocenes and use thereof PHILLIPS PETROLEUM CO (US) 1999-03-03 EP disclosed
EP-0875517-A1 Novel homopolymers of propylene exhibiting more than 50% syndiotacticity and more than 50 wt-% xylene solubles PHILLIPS PETROLEUM COMPANY (US) 1998-11-04 EP disclosed
EP-0849288-A1 Catalyst for polymerization of an olefin, and method for producing an olefin polymer TOSOH CORPORATION (JP) 1998-06-24 EP disclosed
US-5627247-A COMPOUNDS OF CYCLOPENTADIENE OR INDENE WITH FLUORENE AND GROUP IV METALS PHILLIPS PETROLEUM COMPANY (US) 1997-05-06 US disclosed
US-5627118-A CATALYSTS FOR OLEFIN POLYMERIZATION PHILLIPS PETROLEUM COMPANY (US) 1997-05-06 US disclosed
US-5459218-A Containing fluorene ring PHILLIPS PETROLEUM COMPANY (US) 1995-10-17 US disclosed
US-5401817-A Syndiotactic polypropylene PHILLIPS PETROLEUM COMPANY (US) 1995-03-28 US disclosed
EP-0628577-A2 Silyl bridged metallocenes and use thereof PHILLIPS PETROLEUM COMPANY (US) 1994-12-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11766669-B2 Hexahydrocyclopenta[e]-as-indacen-1-yl and octahydrobenzo[e]-as-indacen-1-yl based catalyst complexes and process for use thereof MLX, ZYX, TXN METAP1 3183/4885MAPT 4060/4885KDM4E 585/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.