Water

Water

SCHEMBL715193

O.O=C(O)C(=O)C(=O)O

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL10863045 1.00 CA1 (0.40)
Water SCHEMBL175846 0.95 CA1 (0.36)
Water SCHEMBL27701356 0.95 CA1 (0.36)
Water SCHEMBL27791587 0.95 CA1 (0.36)
SCHEMBL28953 0.94
SCHEMBL1122402 0.94 CA1 (0.44)
Water SCHEMBL27808824 0.91 LDHA (0.33)
SCHEMBL8523081 0.89
SCHEMBL28790715 0.89
SCHEMBL1649056 0.89

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4746844-A1 PERSONAL CARE COMPOSITIONS Colgate-Palmolive Company (US) 2026-05-27 EP disclosed
EP-4615401-A1 PERSONAL CARE COMPOSITIONS Colgate-Palmolive Company (US) 2025-09-17 EP disclosed
EP-4580591-A1 INTIMATE CARE COMPOSITION WITH POST BIOTIC BLEND Colgate-Palmolive Company (US) 2025-07-09 EP disclosed
WO-2025137098-A1 PERSONAL CARE COMPOSITIONS COLGATE-PALMOLIVE COMPANY (US) 2025-06-26 WO disclosed
US-20250195382-A1 Personal Care Compositions COLGATE-PALMOLIVE COMPANY (US) 2025-06-19 US disclosed
EP-4561524-A1 PERSONAL CARE COMPOSITION WITH POST BIOTIC BLEND Colgate-Palmolive Company (US) 2025-06-04 EP disclosed
US-20250107993-A1 Personal Care Compositions COLGATE-PALMOLIVE COMPANY (US) 2025-04-03 US disclosed
WO-2025043091-A1 PERSONAL CARE COMPOSITIONS COLGATE-PALMOLIVE COMPANY (US) 2025-02-27 WO disclosed
US-12201713-B2 Personal care compositions COLGATE-PALMOLIVE COMPANY (US) 2025-01-21 US disclosed
US-12171850-B2 Personal care compositions COLGATE-PALMOLIVE COMPANY (US) 2024-12-24 US disclosed
US-20210275418-A1 Personal Care Compositions COLGATE-PALMOLIVE COMPANY (US) 2021-09-09 US disclosed
US-20210275419-A1 Personal Care Compositions COLGATE-PALMOLIVE COMPANY (US) 2021-09-09 US disclosed
US-20210230649-A1 Production of Carbon-Based Compounds from Cellulosic Feedstock Fermentation METROPOLITAN WATER RECLAMATION DISTRICT OF GREATER CHICAGO 2021-07-29 US disclosed
WO-2020185654-A1 PERSONAL CARE COMPOSITIONS COLGATE-PALMOLIVE COMPANY (US) 2020-09-17 WO disclosed
US-20120049106-A1 MALEIMIDE-FUNCTIONAL MONOMERS IN AMORPHOUS FORM DESIGNER MOLECULES, INC. (US) 2012-03-01 US disclosed
WO-2011127933-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2011-10-20 WO disclosed
WO-2011116050-A2 CURING AGENTS FOR EPOXY RESINS DESIGNER MOLECULES, INC. (US) 2011-09-22 WO disclosed
US-8013104-B2 Thermosetting hyperbranched compositions and methods for use thereof DESIGNER MOLECULES, INC. (US) 2011-09-06 US disclosed
US-8008419-B2 Siloxane monomers and methods for use thereof DESIGNER MOLECULES, INC. (US) 2011-08-30 US disclosed
US-20110152466-A1 AMIDE-EXTENDED CROSSLINKING COMPOUNDS AND METHODS FOR USE THEREOF DESIGNER MOLECULES, INC. (US) 2011-06-23 US disclosed