Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PNP | P00491 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 2/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HINT1 | P49773 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NT5E | P21589 | 5/20 | 0.35 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18490329 | 0.84 | TAS1R3 (0.49) | TAS1R3TAS1R1MEN1KMT2ATSHR | |
| SCHEMBL7158740 | 0.80 | PRMT6 (0.41) | — | |
| SCHEMBL7162040 | 0.76 | RNASE1 (0.47) | MEN1KMT2AALDH1A1NT5E | |
| SCHEMBL7162782 | 0.76 | NT5E (0.47) | MEN1KMT2ANT5E | |
| SCHEMBL7157425 | 0.75 | NT5E (0.40) | MEN1KMT2AALDH1A1NT5E | |
| SCHEMBL7162036 | 0.75 | MEN1 (0.38) | MEN1KMT2ATSHRALDH1A1NT5E | |
| SCHEMBL16214948 | 0.73 | TAS1R3 (0.44) | TAS1R3TAS1R1MEN1KMT2ATSHR | |
| SCHEMBL7165048 | 0.73 | ALDH1A1 (0.36) | MEN1KMT2AALDH1A1NT5E | |
| SCHEMBL15929488 | 0.73 | TAS1R3 (0.42) | TAS1R3TAS1R1MEN1KMT2ATSHR | |
| SCHEMBL7037107 | 0.72 | NT5E (0.44) | MEN1KMT2AALDH1A1NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747389-B1 | 3'-SUBSTITUTED NUCLEOSIDE DERIVATIVES | TAIHO PHARMACEUTICAL CO LTD (JP) | 2003-09-10 | — | — | EP | disclosed |
| US-RE38090-E1 | Antitumor activity; useful for treatment and prevention of cancers | Matsuda, Akira (JP) | 2003-04-22 | — | — | US | disclosed |
| EP-0747389-A1 | 3'-SUBSTITUTED NUCLEOSIDE DERIVATIVES | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1996-12-11 | — | — | EP | disclosed |