SCHEMBL716124

SCHEMBL716124

Cc1[c]c2ccccc(C(C)C)c-2c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 3/20 0.38
GABRB2 P47870 2/20 0.38
LMNA P02545 4/20 0.34
FAAH O00519 2/20 0.34
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
GABRG2 P18507 2/20 0.34
GABRB3 P28472 2/20 0.34
SLC6A2 P23975 2/20 0.34
HTR2B P41595 2/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
HPGD P15428 1/20 0.34
TSHR P16473 1/20 0.34
GABRB1 P18505 1/20 0.34
PTGS1 P23219 1/20 0.34
HTR2C P28335 1/20 0.34
GABRA5 P31644 1/20 0.34
GABRA3 P34903 1/20 0.34
GABRA2 P47869 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL820365 0.80 CA1 (0.35) GABRA1GABRB2LMNAFAAHCA1
SCHEMBL28611557 0.77 CA1 (0.45) GABRA1GABRB2LMNAFAAHCA1
SCHEMBL712397 0.75 ACHE (0.39) LMNACA1CA2CYP1A2CYP3A4
SCHEMBL8127141 0.73 GABRA1 (0.35) GABRA1GABRB2LMNAFAAHCA1
SCHEMBL714544 0.71 ALDH1A1 (0.40) CA1CA2HPGDCA12CA9
SCHEMBL819700 0.70 GABRA1 (0.36) GABRA1GABRB2LMNAFAAHCA1
SCHEMBL29414063 0.69 GABRA1 (0.55) GABRA1GABRB2LMNAFAAHCA1
SCHEMBL167078 0.69 GABRA1 (0.55) GABRA1GABRB2LMNAFAAHCA1
SCHEMBL3222569 0.68 GABRA1 (0.40) GABRA1GABRB2LMNAFAAHCA1
SCHEMBL8144266 0.67 LMNA (0.33) GABRA1GABRB2LMNAFAAHCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8357765-B2 Process for producing catalyst component for addition polymerization SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-01-22 US disclosed
US-8288490-B2 Process for producing catalyst component for addition polymerization SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-16 US disclosed
US-20120053306-A1 PROCESS FOR PRODUCING CATALYST COMPONENT FOR ADDITION POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-03-01 US disclosed
US-20120053311-A1 PROCESS FOR PRODUCING CATALYST COMPONENT FOR ADDITION POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120053306-A1 PROCESS FOR PRODUCING CATALYST COMPONENT FOR ADDITION POLYMERIZATION PPOX, SOD1, AP1M1 GABRA1 856/4885GABRB2 1219/4885LMNA 4156/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.