Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | RXRB | P28702 | 1/20 | 0.30 |
| ▸ | RXRG | P48443 | 1/20 | 0.30 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.30 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.30 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3692619 | 0.86 | ELANE (0.39) | ELANEATMTDP1ALDH1A1CYP1A2 | |
| SCHEMBL717322 | 0.83 | SMN1; SMN2 (0.33) | ELANEMAOBALDH1A1CYP2C19KDM4E | |
| SCHEMBL712791 | 0.81 | MAOB (0.35) | ELANEMAOBALDH1A1GAA | |
| SCHEMBL10584097 | 0.80 | ELANE (0.38) | ELANEATMTDP1MAOAMAOB | |
| SCHEMBL2274238 | 0.80 | THRB (0.40) | ELANEATMTDP1MAOAMAOB | |
| SCHEMBL771097 | 0.74 | ALDH1A1 (0.44) | TDP1ALDH1A1 | |
| SCHEMBL31069899 | 0.74 | KCNN4 (0.38) | ELANEATMTDP1MAOAMAOB | |
| SCHEMBL14827332 | 0.74 | LMNA (0.40) | ELANEATMTDP1MAOAMAOB | |
| SCHEMBL10899304 | 0.74 | ALDH1A1 (0.48) | TDP1ALDH1A1 | |
| SCHEMBL28282211 | 0.74 | TDP1 (0.42) | ELANEATMTDP1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2657304-B1 | AZO DYE, OCULAR LENS MATERIAL, METHOD FOR PRODUCING OCULAR LENS MATERIAL, AND OCULAR LENS | MENICON CO LTD (JP) | 2022-12-07 | — | — | EP | disclosed |
| CN-109524617-A | Activation of metal in the passive state method and its purposes | 泰克年研究发展基金会公司 | 2019-03-26 | — | — | CN | disclosed |
| US-9017716-B2 | Ophthalmic lens | MENICON CO., LTD. (JP) | 2015-04-28 | — | — | US | disclosed |
| EP-2657304-A1 | AZO DYE, OCULAR LENS MATERIAL, METHOD FOR PRODUCING OCULAR LENS MATERIAL, AND OCULAR LENS | Menicon Co., Ltd. (JP) | 2013-10-30 | — | — | EP | disclosed |
| US-20130202551-A1 | IONIC COMPOUND, COMPOSITION, CURED MATERIAL, HYDROGEL AND OPHTHALMIC LENS | MENICON CO., LTD. (JP) | 2013-08-08 | — | — | US | disclosed |
| EP-2581394-A1 | IONIC COMPOUND, COMPOSITION, CURED PRODUCT, HYDROGEL, AND OCULAR LENS | Menicon Co., Ltd. (JP) | 2013-04-17 | — | — | EP | disclosed |
| EP-2514791-A1 | ANTHRAQUINONE PIGMENT, OCULAR LENS MATERIAL USING SAME, OCULAR LENS MATERIAL MANUFACTURING METHOD, AND OCULAR LENS | Menicon Co., Ltd. (JP) | 2012-10-24 | — | — | EP | disclosed |
| US-20120148519-A1 | OPHTHALMIC LENS | MENICON CO., LTD. (JP) | 2012-06-14 | — | — | US | disclosed |
| US-8124668-B2 | Silicone-containing ocular lens material with high safety and preparing method thereof | MENICON CO., LTD. (JP) | 2012-02-28 | — | — | US | disclosed |
| EP-2180366-A1 | Silicone-containing ocular lens material with high safety and preparing method thereof | MENICON CO., LTD. (JP) | 2010-04-28 | — | — | EP | disclosed |
| US-20060142410-A1 | Silicone-containing ocular lens material with high safety and preparing method thereof | MENICON CO., LTD. (JP) | 2006-06-29 | — | — | US | disclosed |
| US-7037954-B2 | Ocular lens material | MENICON CO., LTD. (JP) | 2006-05-02 | — | — | US | disclosed |
| EP-1582910-A1 | HIGHLY SAFE SILICONE-CONTAINING MATERIAL FOR OCULAR LENS AND PROCESS FOR PRODUCING THE SAME | MENICON CO., LTD. (JP) | 2005-10-05 | — | — | EP | disclosed |
| EP-1197782-B1 | MATERIAL FOR OCULAR LENS | MENICON CO LTD (JP) | 2004-06-02 | — | — | EP | disclosed |
| US-20040039077-A1 | Ocular lens material | MENICON CO., LTD. | 2004-02-26 | — | — | US | disclosed |
| US-6638991-B2 | Lens material comprising a copolymer derived from a polysiloxane endcapped with acrylated urethane groups, a silicon-containing alkyl methacrylate, a hydrophilic monomer, and a crosslinking monomer; oxygen permeability, strength | MENICON CO., LTD. (JP) | 2003-10-28 | — | — | US | disclosed |
| US-20020198280-A1 | Material for ocular lens | MENICON CO., LTD. (JP) | 2002-12-26 | — | — | US | disclosed |
| EP-1197782-A1 | MATERIAL FOR OCULAR LENS | MENICON CO., LTD. (JP) | 2002-04-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120148519-A1 | OPHTHALMIC LENS | AQP4, CRYAA, UACA | ELANE 2005/4885ATM 1780/4885TDP1 3943/4885 |
| US-20130202551-A1 | IONIC COMPOUND, COMPOSITION, CURED MATERIAL, HYDROGEL AND OPHTHALMIC LENS | CRYZ, CRYAA, VIL1 | ELANE 665/4885ATM 2931/4885TDP1 4759/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.