Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10483727 | 0.85 | ELANE (1.00) | ELANEPRTN3 | |
| SCHEMBL6337153 | 0.84 | ELANE (0.77) | ELANEPRTN3 | |
| SCHEMBL22369614 | 0.82 | ELANE (0.86) | ELANEPRTN3 | |
| SCHEMBL7219090 | 0.82 | ELANE (0.74) | ELANEPRTN3 | |
| SCHEMBL7183398 | 0.82 | ELANE (0.74) | ELANEPRTN3 | |
| SCHEMBL31531294 | 0.82 | ELANE (0.74) | ELANEPRTN3 | |
| SCHEMBL10483766 | 0.81 | ELANE (1.00) | ELANEPRTN3 | |
| SCHEMBL65265 | 0.79 | MAPT (0.71) | ELANE | |
| SCHEMBL30259514 | 0.79 | ELANE (0.70) | ELANEPRTN3 | |
| SCHEMBL5081863 | 0.79 | POLB (0.48) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116874396-A | Method for preparing high-purity cilansetron sodium | 南京福美瑞信科技有限公司 | 2023-10-13 | — | — | CN | claimed |
| CN-113693064-A | Disinfectant and preparation method and application thereof | 北京擎科生物科技有限公司 | 2021-11-26 | — | — | CN | claimed |
| CN-116874396-A | Method for preparing high-purity cilansetron sodium | 南京福美瑞信科技有限公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-113693064-A | Disinfectant and preparation method and application thereof | 北京擎科生物科技有限公司 | 2021-11-26 | — | — | CN | disclosed |
| CN-113693064-A | Disinfectant and preparation method and application thereof | 北京擎科生物科技有限公司 | 2021-11-26 | — | — | CN | disclosed |
| EP-1083167-B1 | Process for the preparation of aryl carboxylate esters | EASTMAN CHEM CO (US) | 2003-04-16 | — | — | EP | disclosed |
| US-6448430-B1 | BY REACTION OF A PHENOL WITH A CARBOXYLIC ACID IN THE PRESENCE OF TRIFLUOROACETIC ACID (TFA) AND TRIFLUOROACETIC ANHYDRIDE (TFAA); RELATIVELY LOW TEMPERATURE | EASTMAN CHEMICAL COMPANY | 2002-09-10 | — | — | US | disclosed |
| EP-1083167-A1 | Process for the preparation of aryl carboxylate esters | EASTMAN CHEMICAL COMPANY (US) | 2001-03-14 | — | — | EP | disclosed |