Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.45 |
| ▸ | METAP1 | P53582 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2880191 | 0.87 | LMNA (0.54) | LMNAPOLBRXFP1BRD9METAP1 | |
| SCHEMBL29683229 | 0.84 | RXFP1 (0.43) | LMNAPOLBRXFP1BRD9METAP1 | |
| SCHEMBL21046968 | 0.84 | RXFP1 (0.43) | LMNAPOLBRXFP1BRD9METAP1 | |
| SCHEMBL6346054 | 0.84 | RXFP1 (0.43) | SIGMAR1LMNAPOLBRXFP1BRD9 | |
| SCHEMBL27913236 | 0.84 | RXFP1 (0.46) | LMNAPOLBRXFP1BRD9METAP1 | |
| SCHEMBL4824683 | 0.82 | HPGD (0.50) | SIGMAR1LMNAMEN1KMT2ASMN1; SMN2 | |
| Water SCHEMBL27694505 | 0.81 | LMNA (0.47) | LMNAPOLBRXFP1BRD9METAP1 | |
| SCHEMBL30048786 | 0.81 | RXFP1 (0.43) | LMNAPOLBRXFP1BRD9METAP1 | |
| SCHEMBL1534089 | 0.81 | NPC1 (0.58) | LMNAPOLBRXFP1BRD9RAB9A | |
| SCHEMBL1794452 | 0.81 | LMNA (0.49) | LMNAPOLBRXFP1BRD9METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140135499-A1 | METHODS FOR THE TOTAL CHEMICAL SYNTHESIS OF ENANTIOMERICALLY-PURE 7-(2'-TRIMETHYLSILYL) ETHYL CAMPTOTHECIN | BIONUMERIK PHARMACEUTICALS, INC. | 2014-05-15 | — | — | US | claimed |
| US-8722886-B1 | Methods for the total chemical synthesis of enantiomerically-pure 7-(2′-trimethylsilyl)ethyl camptothecin | BIONUMERIK PHARMACEUTICALS, INC. (US) | 2014-05-13 | — | — | US | claimed |
| EP-0841337-B1 | Substituted 7,12-dioxabenzo(a)anthracene derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-09-05 | — | — | EP | claimed |
| EP-0841337-A1 | Substituted 7,12-dioxabenzo(a)anthracene derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-05-13 | — | — | EP | claimed |
| US-20260085034-A1 | N-(BENZHYDRYL)CYCLOALKYLCARBOXAMIDE DERIVATIVES AS INHIBITORS OF GLYCOGEN SYNTHASE 1 (GYS1) AND METHODS OF USE THEREOF | HERCULES CAPITAL, INC., AS AGENT | 2026-03-26 | — | — | US | disclosed |
| US-12497385-B2 | Photoprotective compositions containing Malassezia-derived compounds and/or chemical analogs thereof | VERSICOLOR TECHNOLOGIES, LLC (US) | 2025-12-16 | — | — | US | disclosed |
| US-12428374-B2 | Malassezin and analogs thereof as skin brightening agents | VERSICOLOR TECHNOLOGIES, LLC (US) | 2025-09-30 | — | — | US | disclosed |
| EP-4587422-A1 | N-(BENZHYDRYL)CYCLOALKYLCARBOXAMIDE DERIVATIVES AS INHIBITORS OF GLYCOGEN SYNTHASE 1 (GYS1) AND METHODS OF USE THEREOF | Maze Therapeutics, Inc. (US) | 2025-07-23 | — | — | EP | disclosed |
| EP-4578512-A2 | MALASSEZIN AND ANALOGS THEREOF AS SKIN BRIGHTENING AGENTS | VERSICOLOR TECHNOLOGIES, LLC (US) | 2025-07-02 | — | — | EP | disclosed |
| EP-4545147-A2 | PHOTOPROTECTIVE COMPOSITIONS CONTAINING MALASSEZIA-DERIVED COMPOUNDS AND/OR CHEMICAL ANALOGS THEREOF | VERSICOLOR TECHNOLOGIES, LLC (US) | 2025-04-30 | — | — | EP | disclosed |
| EP-3426658-B1 | MALASSEZIN AND ANALOGS THEREOF AS SKIN BRIGHTENING AGENTS | VERSICOLOR TECH LLC (US) | 2025-01-15 | — | — | EP | disclosed |
| EP-3774811-B1 | PHOTOPROTECTIVE COMPOSITIONS CONTAINING MALASSEZIA-DERIVED COMPOUNDS AND/OR CHEMICAL ANALOGS THEREOF | VERSICOLOR TECH LLC (US) | 2024-12-18 | — | — | EP | disclosed |
| EP-1408970-A1 | INDOLINES AND TETRAHYDRO-QUINOLINES AS PRODRUGS FOR TUMOUR TREATMENT | THE SCHOOL OF PHARMACY, UNIVERSITY OF LONDON (GB) | 2004-04-21 | — | — | EP | disclosed |
| WO-2002067937-A1 | INDOLINE AND TETRAHYDRO-QUINOLINES AS PRODRUGS FOR TUMOUR TREATMENT | SCHOOL OF PHARMACY, UNIVERSITY OF LONDON (GB) | 2002-09-06 | — | — | WO | disclosed |
| EP-0739903-B1 | CARBAMOYLMETHYLUREA DERIVATIVE | SHIONOGI & CO (JP) | 2002-01-23 | — | — | EP | disclosed |
| EP-0841337-B1 | Substituted 7,12-dioxabenzo(a)anthracene derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-09-05 | — | — | EP | disclosed |
| US-5807882-A | ANTITUMOR AGENTS | ADIR ET COMPAGNIE (FR) | 1998-09-15 | — | — | US | disclosed |
| EP-0841337-A1 | Substituted 7,12-dioxabenzo(a)anthracene derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-05-13 | — | — | EP | disclosed |
| US-5739162-A | ANTAGONIST FOR GASTRIN AND/OR CHOLECYSTOKININ B-NOT A-RECEPTORS; SIDE EFFECT REDUCTION; ANTIULCER AGENTS; OPIOD-ENHANCING ANALGESICS; GASTROINTESTINAL DISORDERS; ANXIOLYTIC AGENTS | SHIONOGI & CO., LTD. (JP) | 1998-04-14 | — | — | US | disclosed |
| EP-0739903-A1 | CARBAMOYLMETHYLUREA DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1996-10-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12497385-B2 | Photoprotective compositions containing Malassezia-derived compounds and/or chemical analogs thereof | TYR, AHR, MC1R | SIGMAR1 4824/4885LMNA 3050/4885POLB 2455/4885 |
| US-12428374-B2 | Malassezin and analogs thereof as skin brightening agents | TYR, MC1R, AHR | SIGMAR1 4546/4885LMNA 4108/4885POLB 4416/4885 |
| US-20260085034-A1 | N-(BENZHYDRYL)CYCLOALKYLCARBOXAMIDE DERIVATIVES AS INHIBITORS OF GLYCOGEN SYNTHASE 1 (GYS1) AND METHODS OF USE THEREOF | GYS2, GYS1, PYGL | SIGMAR1 1494/4885LMNA 65/4885POLB 2183/4885 |
| US-20140135499-A1 | METHODS FOR THE TOTAL CHEMICAL SYNTHESIS OF ENANTIOMERICALLY-PURE 7-(2'-TRIMETHYLSILYL) ETHYL CAMPTOTHECIN | NT5C, PAICS, PDE10A | SIGMAR1 704/4885LMNA 43/4885POLB 2254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.