Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MASP2 | O00187 | 1/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7047979 | 0.93 | TBXA2R (0.41) | ALDH1A1MAPTKDM4ELMNATBXA2R | |
| SCHEMBL7044843 | 0.90 | L3MBTL1 (0.39) | ALDH1A1MAPTLMNARAB9ATBXA2R | |
| SCHEMBL7558531 | 0.88 | DAGLA (0.39) | MEN1KMT2ALMNAMAPK1RAB9A | |
| SCHEMBL7047180 | 0.82 | P2RX7 (0.37) | DAGLA | |
| SCHEMBL7049295 | 0.79 | DAGLA (0.41) | KMT2AMAPTDAGLA | |
| SCHEMBL7049748 | 0.77 | XDH (0.40) | CACNA1HKMT2AALDH1A1MAPTLMNA | |
| SCHEMBL6467199 | 0.77 | DAGLA (0.41) | LMNAMAPK1RAB9ATBXA2RDAGLA | |
| SCHEMBL7567535 | 0.76 | DAGLA (0.43) | KMT2ALMNADAGLA | |
| SCHEMBL7047182 | 0.76 | DAGLA (0.39) | ALDH1A1MAPK1DAGLA | |
| SCHEMBL7183270 | 0.76 | MGLL (0.40) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6576630-B1 | Alkanoyl substituted benzooxazoles or naphthooxazoles | AXYS PHARMACEUTICALS, INC. | 2003-06-10 | — | — | US | disclosed |