Sugi Predict

Sugi Predict / Compounds / SCHEMBL719007

SCHEMBL719007

SCHEMBL719007

CC(C)(C)[Si](C)(C)OC(C(=O)c1ccccc1)[C@H]1O[C@@H](n2ccc(N)nc2=O)C[C@@H]1O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 2/20 0.43
▸ POLG P54098 2/20 0.38
▸ LMNA P02545 3/20 0.37
▸ CACNA1F O60840 2/20 0.37
▸ ALB P02768 2/20 0.37
▸ MAPT P10636 2/20 0.37
▸ CACNA1D Q01668 2/20 0.37
▸ CACNA1S Q13698 2/20 0.37
▸ CACNA1C Q13936 2/20 0.37
▸ PDE3A Q14432 2/20 0.37
▸ ST6GAL1 P15907 4/20 0.36
▸ P2RY2 P41231 3/20 0.36
▸ P2RY4 P51582 3/20 0.36
▸ P2RY6 Q15077 2/20 0.36
▸ THRB P10828 1/20 0.34
▸ MTOR P42345 1/20 0.34
▸ MDM2 Q00987 1/20 0.34
▸ NCOA1 Q15788 1/20 0.34
▸ NCOA3 Q9Y6Q9 1/20 0.34
▸ NT5E P21589 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7514883 0.88 POLG (0.36) POLBPOLGLMNACACNA1FALB
SCHEMBL718788 0.85 POLB (0.37) POLBPOLGLMNACACNA1FALB
SCHEMBL18817573 0.85 POLB (0.37) POLBPOLGLMNACACNA1FALB
SCHEMBL5200171 0.82 POLB (0.40) POLBPOLGLMNACACNA1FALB
SCHEMBL19642755 0.81 POLB (0.42) POLBPOLGLMNACACNA1FALB
SCHEMBL718524 0.78 POLB (0.45) POLB
SCHEMBL2835834 0.78 POLB (0.45) POLB
SCHEMBL9163280 0.78 POLB (0.45) POLBPOLGLMNACACNA1FALB
SCHEMBL2991280 0.77 POLB (0.47) POLBPOLGLMNACACNA1FALB
SCHEMBL888343 0.76 LMNA (0.38) POLBPOLGLMNACACNA1FALB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11940413-B2 Methods and devices for sequencing nucleic acids in smaller batches IsoPlexis Corporation (US) 2024-03-26 — — US disclosed
US-20240076731-A1 METHODS AND COMPOSITIONS FOR INCORPORATING NUCLEOTIDES QIAGEN SCIENCES, LLC 2024-03-07 — — US disclosed
EP-3743517-B1 SEQUENCING ADDITIVE QIAGEN SCIENCES LLC (US) 2024-03-06 — — EP disclosed
US-20240060128-A1 METHODS AND COMPOSITIONS FOR INCORPORATING NUCLEOTIDES QIAGEN WALTHAM, INC. 2024-02-22 — — US disclosed
US-11866741-B2 Polymerase enzyme from 9°N IsoPlexis Corporation (US) 2024-01-09 — — US disclosed
US-20230407384-A1 METHODS AND COMPOSITIONS FOR INCORPORATING NUCLEOTIDES QIAGEN WALTHAM, INC. 2023-12-21 — — US disclosed
US-11821032-B2 DNA sequencing reaction additive IsoPlexis Corporation (US) 2023-11-21 — — US disclosed
US-11548910-B2 Oligonucleotide production method NISSAN CHEMICAL CORPORATION (JP) 2023-01-10 — — US disclosed
US-11548909-B2 Methods of using nucleotide analogues IsoPlexis Corporation (US) 2023-01-10 — — US disclosed
US-20220315995-A1 THIOL-CONTAINING CLEAVE REAGENTS AND OXIDATIVE WASH QIAGEN WALTHAM, INC. 2022-10-06 — — US disclosed
US-20130301888-A1 Methods And Compositions For Base Calling Nucleic Acids IsoPlexis Corporation 2013-11-14 — — US disclosed
US-8481259-B2 Methods and devices for sequencing nucleic acids in smaller batches INTELLIGENT BIO-SYSTEMS, INC. (US) 2013-07-09 — — US disclosed
US-20130137091-A1 Methods And Compositions For Incorporating Nucleotides INTELLIGENT BIO-SYSTEMS, INC. 2013-05-30 — — US disclosed
US-20120052489-A1 METHODS AND COMPOSITIONS FOR SEQUENCING NUCLEIC ACIDS USING CHARGE INTELLIGENT BIO-SYSTEMS, INC. 2012-03-01 — — US disclosed
US-20110124054-A1 Methods And Compositions For Inhibiting Undesired Cleaving Of Labels INTELLIGENT BIO-SYSTEMS, INC. 2011-05-26 — — US disclosed
US-20100330569-A1 Hydroxymethyl Linkers For Labeling Nucleotides INTELLIGENT BIO-SYSTEMS, INC. 2010-12-30 — — US disclosed
US-20100323350-A1 Methods And Devices For Sequencing Nucleic Acids In Smaller Batches INTELLIGENT BIOSYSTEMS, INC. 2010-12-23 — — US disclosed
US-20100063743-A1 Methods And Compositions For Base Calling Nucleic Acids INTELLIGENT BIO-SYSTEMS, INC. 2010-03-11 — — US disclosed
US-20100035253-A1 Methods And Compositions For Incorporating Nucleotides INTELLIGENT BIO-SYSTEMS, INC. 2010-02-11 — — US disclosed
WO-2009117119-A1 METHODS AND COMPOSITIONS FOR BASE CALLING NUCLEIC ACIDS INTELLIGENT BIO-SYSTEMS, INC. (US) 2009-09-24 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11548909-B2 Methods of using nucleotide analogues NT5C3B, SAMHD1, RNGTT POLB 32/4885POLG 197/4885LMNA 1174/4885
US-11548910-B2 Oligonucleotide production method RNGTT, OSGEP, PHAX POLB 37/4885POLG 169/4885LMNA 2077/4885
US-20240076731-A1 METHODS AND COMPOSITIONS FOR INCORPORATING NUCLEOTIDES NT5C2, NOP2, NT5C3B POLB 44/4885POLG 407/4885LMNA 202/4885
US-20220315995-A1 THIOL-CONTAINING CLEAVE REAGENTS AND OXIDATIVE WASH SAMHD1, UNG, RNGTT POLB 29/4885POLG 225/4885LMNA 3626/4885
US-20230407384-A1 METHODS AND COMPOSITIONS FOR INCORPORATING NUCLEOTIDES NT5C2, NOP2, NT5C3B POLB 44/4885POLG 407/4885LMNA 202/4885
US-11821032-B2 DNA sequencing reaction additive RNGTT, NSUN2, NT5C3B POLB 18/4885POLG 142/4885LMNA 3089/4885
US-20240060128-A1 METHODS AND COMPOSITIONS FOR INCORPORATING NUCLEOTIDES NT5C2, NOP2, NT5C3B POLB 44/4885POLG 407/4885LMNA 202/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.