Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 13/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL2691671 | 0.86 | RIPK1 (0.59) | RIPK1MAPK1 | |
| SCHEMBL10812826 | 0.83 | RIPK1 (0.59) | RIPK1MAPK1 | |
| SCHEMBL9183007 | 0.76 | MAPK1 (0.68) | RIPK1ALDH1A1MAPK1POLBL3MBTL1 | |
| SCHEMBL4499756 | 0.74 | L3MBTL1 (0.60) | ALDH1A1POLBL3MBTL1 | |
| SCHEMBL17055469 | 0.74 | L3MBTL1 (0.56) | ALDH1A1MAPK1POLBBRD9L3MBTL1 | |
| SCHEMBL17055466 | 0.72 | MALT1 (0.53) | ALDH1A1MAPK1POLBBRD9L3MBTL1 | |
| SCHEMBL122207 | 0.72 | MAPK1 (0.76) | RIPK1MAPK1POLB | |
| SCHEMBL10756366 | 0.72 | RIPK1 (0.61) | RIPK1ALDH1A1MAPK1POLB | |
| SCHEMBL10761439 | 0.71 | RIPK1 (0.60) | RIPK1MAPK1 | |
| SCHEMBL10812821 | 0.71 | MAPK1 (0.74) | RIPK1MAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030192070-A1 | COMPOSITION FOR HYBRID SEED PRODUCTION, PROCESS FOR THE PREPARATION OF SUCH COMPOSITION AND USE THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2003-10-09 | — | — | US | claimed |
| US-6645917-B2 | Mixture of potassium 1-(4-chlorophenyl)- and 1-(4-fluoro-3-chlorophenyl)-1,4 dihydro-6-methyl-4-oxopyridazine-3-carboxylate and nonionic surfactant; enhances male sterility; wheat, cereals | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2003-11-11 | — | — | US | disclosed |
| US-6645917-B2 | Mixture of potassium 1-(4-chlorophenyl)- and 1-(4-fluoro-3-chlorophenyl)-1,4 dihydro-6-methyl-4-oxopyridazine-3-carboxylate and nonionic surfactant; enhances male sterility; wheat, cereals | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2003-11-11 | — | — | US | disclosed |
| US-20030192070-A1 | COMPOSITION FOR HYBRID SEED PRODUCTION, PROCESS FOR THE PREPARATION OF SUCH COMPOSITION AND USE THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2003-10-09 | — | — | US | disclosed |
| US-20030192070-A1 | COMPOSITION FOR HYBRID SEED PRODUCTION, PROCESS FOR THE PREPARATION OF SUCH COMPOSITION AND USE THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2003-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030192070-A1 | COMPOSITION FOR HYBRID SEED PRODUCTION, PROCESS FOR THE PREPARATION OF SUCH COMPOSITION AND USE THEREOF | ZP1, KCNK4, NASP | RIPK1 3482/4885ALDH1A1 1593/4885MAPK1 2808/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.