Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK2 | O00142 | 3/20 | 0.35 |
| ▸ | TK1 | P04183 | 1/20 | 0.35 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4949384 | 0.91 | TK2 (0.39) | TK2TK1 | |
| SCHEMBL6851558 | 0.83 | TK1 (0.34) | TK2TK1 | |
| SCHEMBL3300455 | 0.75 | RNASE1 (0.37) | TK2TK1 | |
| SCHEMBL5668664 | 0.72 | TK1 (0.39) | TK2TK1 | |
| SCHEMBL9545108 | 0.72 | TK2 (0.40) | TK2TK1 | |
| SCHEMBL3458558 | 0.71 | SLC28A1 (0.41) | — | |
| SCHEMBL8539644 | 0.69 | LMNA (0.37) | TK2 | |
| SCHEMBL8815300 | 0.69 | SLC5A1 (0.34) | — | |
| SCHEMBL9029503 | 0.67 | P2RY2 (0.41) | — | |
| SCHEMBL9030188 | 0.67 | P2RY2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1346065-A2 | ANTISENSE MODULATION OF SRC-2 EXPRESSION | ISIS PHARMACEUTICALS, INC. (US) | 2003-09-24 | — | — | EP | disclosed |
| WO-2003052072-A2 | ANTISENSE MODULATION OF ESTROGEN RECEPTOR ALPHA EXPRESSION | ISIS PHARMACEUTICALS, INC. (US) | 2003-06-26 | — | — | WO | disclosed |
| WO-2003027327-A1 | ANTISENSE MODULATION OF INTERLEUKIN 8 EXPRESSION | ISIS PHARMACEUTICALS, INC. (US) | 2003-04-03 | — | — | WO | disclosed |
| WO-2002057409-A2 | ANTISENSE MODULATION OF SRC-2 EXPRESSION | ISIS PHARMACEUTICALS, INC. (US) | 2002-07-25 | — | — | WO | disclosed |
| WO-2001052864-A1 | ANTISENSE MODULATION OF COT ONCOGENE EXPRESSION | ISIS PHARMACEUTICALS, INC. (US) | 2001-07-26 | — | — | WO | disclosed |