Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 2/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.30 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.30 |
| ▸ | CCR2 | P41597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5872319 | 0.72 | CES2 (0.39) | CES2P2RX1 | |
| SCHEMBL5872347 | 0.69 | — | — | |
| SCHEMBL17555046 | 0.68 | IKBKB (0.43) | CES2AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL24254714 | 0.65 | RXRA (0.41) | CES2AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL440959 | 0.63 | CES2 (0.58) | CES2 | |
| SCHEMBL18726215 | 0.60 | OPRL1 (0.43) | CES2OPRL1 | |
| SCHEMBL5872356 | 0.60 | IDO1 (0.34) | CES2KDM1A | |
| SCHEMBL4461544 | 0.59 | CES2 (0.48) | CES2P2RX1 | |
| SCHEMBL17563223 | 0.58 | SLC1A3 (0.50) | KDM1AAKR1C3AKR1C2 | |
| SCHEMBL3786224 | 0.57 | RAPGEF4 (0.47) | CES2P2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596891-B1 | Reaction product of fluoroorganic compound and organometallic compound | ENICHEM S.P.A. (IT) | 2003-07-22 | — | — | US | disclosed |
| EP-1013675-B1 | Activating composition of metallocene complexes in the catalysis of (co)polymerization processes of olefins | POLIMERI EUROPA SPA (IT) | 2002-07-31 | — | — | EP | disclosed |
| EP-1013675-A2 | Activating composition of metallocene complexes in the catalysis of (co)polymerization processes of olefins | Enichem S.p.A. (IT) | 2000-06-28 | — | — | EP | disclosed |