Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29184903 | 0.82 | ESR1 (0.46) | TSHRESR1ESR2 | |
| SCHEMBL7206400 | 0.79 | CES2 (0.47) | TSHRALDH1A1SRD5A2FFAR1AKR1C3 | |
| SCHEMBL1199765 | 0.79 | TSHR (0.54) | LMNATYRNR1H4TSHRALDH1A1 | |
| SCHEMBL7924991 | 0.77 | HDAC8 (0.41) | TSHRALDH1A1HSD17B10FFAR1KIF11 | |
| SCHEMBL7199129 | 0.76 | CHRNA7 (0.39) | LMNATSHRALDH1A1SRD5A2FFAR1 | |
| SCHEMBL7203087 | 0.76 | TYR (0.40) | LMNATYRALDH1A1ESR1ESR2 | |
| SCHEMBL3586191 | 0.75 | LMNA (0.52) | LMNATYRNR1H4TSHRALDH1A1 | |
| SCHEMBL20752299 | 0.75 | LMNA (0.52) | LMNATYRNR1H4TSHRALDH1A1 | |
| SCHEMBL3692155 | 0.75 | LMNA (0.52) | LMNATYRNR1H4TSHRALDH1A1 | |
| SCHEMBL10708786 | 0.75 | LMNA (0.52) | LMNATYRNR1H4TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4371982-A2 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX Pharmaceuticals, Inc. (US) | 2024-05-22 | — | — | EP | disclosed |
| EP-3583096-B1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS INC (US) | 2024-03-27 | — | — | EP | disclosed |
| US-20230133667-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS INC (US) | 2023-05-04 | — | — | US | disclosed |
| US-20230133667-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS INC (US) | 2023-05-04 | — | — | US | disclosed |
| CN-110520413-B | Macrocyclic broad spectrum antibiotics | 阿奇克斯制药公司 | 2023-02-17 | — | — | CN | disclosed |
| US-20210198316-A9 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | CHARLES RIVER DISCOVERY RESEARCH SERVICES UK LIMITED (GB) | 2021-07-01 | — | — | US | disclosed |
| US-20210198316-A9 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | CHARLES RIVER DISCOVERY RESEARCH SERVICES UK LIMITED (GB) | 2021-07-01 | — | — | US | disclosed |
| US-6605730-B2 | 3-(2-Thienyl)-5-phenyl-1H-pyrazole compounds of given formula | NIHON BAYER AGROCHEM K.K. (JP) | 2003-08-12 | — | — | US | disclosed |
| US-20030028034-A1 | Nematicidal pyrazoles | WADA KATSUAKI (JP) | 2003-02-06 | — | — | US | disclosed |
| US-6310049-B1 | 3-(2-THIENYL),5-(SUBSTITUTED PHENYL)-1H-PYRAZOLES AND 3-(SUBSTITUTED PHENYL),5-(2-THIENYL)-1H-PYRAZOLES OF GIVEN FORMULA; ANTHELMINTICS | NIHON BAYER AGROCHEM K.K. (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-1104418-A2 | NEMATICIDAL PYRAZOLES | NIHON BAYER AGROCHEM K.K. (JP) | 2001-06-06 | — | — | EP | disclosed |
| WO-2000009500-A2 | NEMATICIDAL PYRAZOLES | NIHON BAYER AGROCHEM K.K. (JP) | 2000-02-24 | — | — | WO | disclosed |
| EP-0360091-B1 | PROCESS FOR THE PREPARATION OF ALKYL-SUBSTITUTED CINNAMIC ALDEHYDES | BASF Aktiengesellschaft (DE) | 1992-09-02 | — | — | EP | disclosed |
| US-4996365-A | Preparation of alkyl-substituted cinnamaldehydes | BASF AKTIENGESELLSCHAFT (DE) | 1991-02-26 | — | — | US | disclosed |
| EP-0360091-A2 | Process for the preparation of alkyl-substituted cinnamic aldehydes | BASF Aktiengesellschaft (DE) | 1990-03-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210198316-A9 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | MRPL21, PEPD, CTSC | LMNA 1857/4885TYR 1217/4885NR1H4 3941/4885 |
| US-20230133667-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | MRPL21, PEPD, CTSC | LMNA 1857/4885TYR 1217/4885NR1H4 3941/4885 |
| US-20030028034-A1 | Nematicidal pyrazoles | CBR3, CBR1, CCR4 | LMNA 4048/4885TYR 789/4885NR1H4 731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.