Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 3/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.33 |
| ▸ | RELA | Q04206 | 3/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7207993 | 0.97 | NFKB1 (0.32) | NFKB1NFKB2RELADRD2DRD4 | |
| SCHEMBL8035083 | 0.78 | DRD2 (0.35) | NFKB1NFKB2RELADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL8970254 | 0.77 | DRD2 (0.34) | NFKB1NFKB2RELADRD2DRD4 | |
| SCHEMBL7209888 | 0.75 | CA2 (0.49) | — | |
| SCHEMBL7203555 | 0.74 | NFKB1 (0.44) | NFKB1NFKB2RELADRD2DRD4 | |
| SCHEMBL5697279 | 0.71 | PRKAB2 (0.34) | — | |
| SCHEMBL3290338 | 0.70 | PRKAB2 (0.41) | — | |
| SCHEMBL3290331 | 0.67 | PRKAB2 (0.41) | — | |
| SCHEMBL8045568 | 0.66 | NFKB1 (0.68) | NFKB1NFKB2RELADRD2DRD4 | |
| SCHEMBL7209043 | 0.65 | L3MBTL1 (0.35) | DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714396-B1 | VASOCONTRICTIVE DIHYDROBENZOPYRAN DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2003-12-10 | — | — | EP | claimed |
| EP-0714396-B1 | VASOCONTRICTIVE DIHYDROBENZOPYRAN DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2003-12-10 | — | — | EP | disclosed |