Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.66 |
| ▸ | NPC1 | O15118 | 8/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | CETP | P11597 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL295136 | 0.92 | NPC1 (0.69) | RAB9ANPC1EPHX2 | |
| Hydrogen Sulfide SCHEMBL5919025 | 0.90 | NPC1 (0.67) | RAB9ANPC1EPHX2 | |
| Hydrochloric Acid SCHEMBL28989899 | 0.90 | NPC1 (0.67) | RAB9ANPC1EPHX2 | |
| SCHEMBL1990363 | 0.84 | NPC1 (0.69) | RAB9ANPC1EPHX2 | |
| Pyrazine SCHEMBL9234910 | 0.84 | NPC1 (0.59) | RAB9ANPC1EPHX2 | |
| SCHEMBL7202886 | 0.81 | NPC1 (0.60) | RAB9ANPC1TSHREPHX2 | |
| SCHEMBL5120704 | 0.79 | RAB9A (1.00) | RAB9ANPC1 | |
| SCHEMBL14771799 | 0.79 | NPC1 (0.62) | RAB9ANPC1EPHX2 | |
| SCHEMBL15064868 | 0.79 | NPC1 (0.54) | RAB9ANPC1TSHREPHX2CETP | |
| SCHEMBL693305 | 0.79 | NPC1 (0.67) | RAB9ANPC1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030008814-A1 | Pseudomycin phosphate prodrugs | ELI LILLY AND COMPANY | 2003-01-09 | — | — | US | disclosed |
| US-20030008814-A1 | Pseudomycin phosphate prodrugs | ELI LILLY AND COMPANY | 2003-01-09 | — | — | US | disclosed |
| WO-2001041534-A3 | PSEUDOMYCIN PHOSPHATE PRODRUGS | LILLY CO ELI (US) | 2001-11-22 | — | — | WO | disclosed |
| WO-2001041534-A2 | PSEUDOMYCIN PHOSPHATE PRODRUGS | ELI LILLY AND COMPANY (US) | 2001-06-14 | — | — | WO | disclosed |
| WO-2001041534-A2 | PSEUDOMYCIN PHOSPHATE PRODRUGS | ELI LILLY AND COMPANY (US) | 2001-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030008814-A1 | Pseudomycin phosphate prodrugs | PMM2, ME1, BPGM | RAB9A 1985/4885NPC1 1736/4885TSHR 3948/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.