Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8609683 | 0.90 | SMN1; SMN2 (0.44) | LMNASMN1; SMN2MAPTMAPK1KDM4E | |
| SCHEMBL7197145 | 0.81 | SMN1; SMN2 (0.49) | LMNASMN1; SMN2SIRT1CHRNA7KMT2A | |
| SCHEMBL5378322 | 0.73 | GABRA1 (0.40) | LMNAMAPTMAPK1KDM4EALDH1A1 | |
| SCHEMBL28694886 | 0.73 | LMNA (0.35) | LMNAMAPTMAPK1KMT2AMEN1 | |
| SCHEMBL11399244 | 0.73 | GABRA1 (0.32) | — | |
| SCHEMBL11598660 | 0.73 | GABRA1 (0.32) | — | |
| SCHEMBL795029 | 0.71 | SIRT1 (0.54) | LMNASMN1; SMN2MAPTMAPK1KDM4E | |
| SCHEMBL2575108 | 0.69 | ALDH1A1 (0.41) | LMNASMN1; SMN2MAPTMAPK1KDM4E | |
| SCHEMBL28695134 | 0.69 | ALDH1A1 (0.46) | LMNASMN1; SMN2MAPTMAPK1KDM4E | |
| SCHEMBL3897205 | 0.69 | SIRT1 (0.52) | LMNASMN1; SMN2MAPTMAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6586376-B1 | Sterically hindered polyol ester and polyphenyl thioether, oxidation resistance; jet turbine engines | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY | 2003-07-01 | — | — | US | disclosed |
| US-6191080-B1 | MIXTURE OF POLYOL ESTERS, MIXTURE OF POLYPHENYLENE ETHER AND POLYOL ESTER AND POLYPHENYLENE THIOETHERS | TONEN CORPORATION (JP) | 2001-02-20 | — | — | US | disclosed |