Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | XIAP | P98170 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7206928 | 0.77 | FABP3 (0.41) | — | |
| SCHEMBL7206347 | 0.77 | GABRA1 (0.43) | HPGD | |
| SCHEMBL7212859 | 0.76 | AKR1B1 (0.45) | HPGDMAPTKDM4EPOLBALDH1A1 | |
| SCHEMBL7206905 | 0.76 | NPC1 (0.30) | ALDH1A1 | |
| SCHEMBL7207814 | 0.74 | NPC1 (0.39) | MAPK1 | |
| SCHEMBL2361439 | 0.73 | GSK3B (0.42) | — | |
| SCHEMBL7541652 | 0.71 | RAB9A (0.52) | HPGDMAPTKDM4EALDH1A1MAPK1 | |
| SCHEMBL7206902 | 0.69 | TDP1 (0.41) | POLBALDH1A1 | |
| SCHEMBL1395973 | 0.69 | NOS3 (0.34) | ALDH1A1 | |
| SCHEMBL12214120 | 0.67 | KDM4E (0.42) | HPGDMAPTKDM4EPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0841913-B1 | USE OF SULFAMIC ACID DERIVATIVES, ACYL SULFONAMIDES OR SULFONYL CARBAMATES FOR THE MANUFACTURE OF A MEDICAMENT FOR LOWERING LIPOPROTEIN LEVELS | WARNER LAMBERT CO (US) | 2003-02-05 | — | — | EP | claimed |