Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 4/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL717755 | 0.81 | MAPT (0.38) | ALDH1A1CYP2C19CYP3A4NPC1RAB9A | |
| SCHEMBL721004 | 0.81 | NPC1 (0.52) | ALDH1A1CYP2C19CYP3A4CYP2C9NPC1 | |
| SCHEMBL285489 | 0.78 | TGM2 (0.46) | ALDH1A1CYP2C19CYP3A4CYP2C9NPC1 | |
| SCHEMBL719426 | 0.77 | TGM2 (0.48) | ALDH1A1CYP2C19CYP3A4CYP2C9NPC1 | |
| SCHEMBL300158 | 0.77 | CYP2C19 (0.42) | ALDH1A1CYP2C19CYP3A4CYP2C9NPC1 | |
| SCHEMBL718737 | 0.76 | CYP2C19 (0.37) | ALDH1A1CYP2C19CYP3A4CYP2C9NPC1 | |
| SCHEMBL5396951 | 0.73 | ALDH1A1 (0.58) | ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A | |
| SCHEMBL285727 | 0.72 | THRB (0.50) | ALDH1A1CYP2C19CYP3A4CYP2C9HTT | |
| SCHEMBL285398 | 0.70 | THRB (0.48) | ALDH1A1CYP2C19CYP3A4CYP2C9SMN1; SMN2 | |
| SCHEMBL30758297 | 0.70 | CYP2C19 (0.59) | ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8729203-B2 | Polymer composition | CONTAMAC LIMITED (GB) | 2014-05-20 | — | — | US | disclosed |
| US-20120053313-A1 | POLYMER COMPOSITION | CONTAMAC LIMITED (GB) | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053313-A1 | POLYMER COMPOSITION | UACA, CRYAA, CRYZ | ALDH1A1 3560/4885CYP2C19 1029/4885CYP3A4 2502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.