Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 1/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 7/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.39 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7206388 | 0.86 | TSHR (0.41) | ALDH1A1MEN1KMT2AL3MBTL1GAA | |
| SCHEMBL7211116 | 0.75 | RAB9A (0.51) | ALDH1A1RAB9ANPC1ABCB1KEAP1 | |
| SCHEMBL7206345 | 0.73 | GABRA1 (0.41) | MEN1KMT2ATSHR | |
| SCHEMBL7207547 | 0.72 | L3MBTL1 (0.43) | ALDH1A1L3MBTL1MAPTTSHR | |
| SCHEMBL7212819 | 0.71 | TTR (0.53) | MEN1KMT2AL3MBTL1GAAMAPT | |
| SCHEMBL7211973 | 0.69 | AKR1C1 (0.45) | ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL7207786 | 0.69 | CHRM2 (0.41) | ALDH1A1MEN1KMT2AKCNH2TSHR | |
| SCHEMBL4161434 | 0.68 | KCNH2 (0.49) | CYP1A1CYP1B1ALDH1A1RAB9ANPC1 | |
| SCHEMBL27889179 | 0.67 | RECQL (0.62) | CYP1A1CYP1B1ALDH1A1RAB9ANPC1 | |
| SCHEMBL11859611 | 0.67 | MAPT (0.53) | CYP1A1CYP1B1ALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0841913-B1 | USE OF SULFAMIC ACID DERIVATIVES, ACYL SULFONAMIDES OR SULFONYL CARBAMATES FOR THE MANUFACTURE OF A MEDICAMENT FOR LOWERING LIPOPROTEIN LEVELS | WARNER LAMBERT CO (US) | 2003-02-05 | — | — | EP | claimed |