Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 5/20 | 0.58 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.47 |
| ▸ | IDH1 | O75874 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
| ▸ | ACP3 | P15309 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30070890 | 1.00 | PIN1 (0.58) | PIN1KCNQ2IDH1IDO1ALDH1A1 | |
| SCHEMBL31391124 | 0.89 | ALDH1A1 (0.51) | PIN1IDO1ALDH1A1CRBNTAS1R3 | |
| SCHEMBL13240611 | 0.89 | ALDH1A1 (0.51) | PIN1IDO1ALDH1A1CRBNTAS1R3 | |
| SCHEMBL2994517 | 0.89 | ALDH1A1 (0.51) | PIN1IDO1ALDH1A1CRBNTAS1R3 | |
| SCHEMBL2994523 | 0.89 | ALDH1A1 (0.51) | PIN1IDO1ALDH1A1CRBNTAS1R3 | |
| SCHEMBL4830828 | 0.84 | PIN1 (0.62) | PIN1KCNQ2IDO1PDPK1CRBN | |
| SCHEMBL907688 | 0.82 | PIN1 (0.60) | PIN1KCNQ2IDO1PDPK1ACP3 | |
| SCHEMBL2790690 | 0.82 | PIN1 (0.60) | PIN1KCNQ2IDO1PDPK1ACP3 | |
| SCHEMBL12431131 | 0.82 | PIN1 (0.60) | PIN1KCNQ2IDO1PDPK1ACP3 | |
| SCHEMBL1400973 | 0.82 | PIN1 (0.60) | PIN1KCNQ2IDO1PDPK1ACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115466209-A | Synthesis method of ropinirole cyclopentanoindolone impurity | 南通大学 | 2022-12-13 | — | — | CN | claimed |
| CN-115466209-A | Synthesis method of ropinirole cyclopentanoindolone impurity | 南通大学 | 2022-12-13 | — | — | CN | disclosed |
| CN-102746239-B | Uracil or thymine derivatives for the treatment of hepatitis C | ABBVIE INC. (BS) | 2016-02-10 | — | — | CN | disclosed |
| CN-104628654-A | ANTI-INFECTIVE PYRIMIDINES AND USES THEREOF | ABBVIE BAHAMAS LTD | 2015-05-20 | — | — | CN | disclosed |
| CN-104628655-A | ANTI-INFECTIVE PYRIMIDINES AND USES THEREOF | ABBVIE BAHAMAS LTD | 2015-05-20 | — | — | CN | disclosed |
| CN-101842360-B | Anti-infective pyrimidines and uses thereof | ABBVIE BAHAMAS LTD | 2014-12-17 | — | — | CN | disclosed |
| US-6552044-B2 | Dopamine receptors | H. LUNDBECK A/S (DK) | 2003-04-22 | — | — | US | disclosed |
| EP-0946542-B1 | INDANE OR DIHYDROINDOLE DERIVATIVES | LUNDBECK & CO AS H (DK) | 2002-10-09 | — | — | EP | disclosed |
| US-6352988-B2 | HIGH AFFINITY FOR D4 RECEPTORS; TREATMENT OF SCHIZOPHRENIA, OTHER PSYCHOSES, ANXIETY DISORDERS, DEPRESSION, ALCOHOL ABUSE, IMPULSE CONTROL DISORDERS, AGGRESSION | H. LUNDBECK A/S (DK) | 2002-03-05 | — | — | US | disclosed |
| US-20010021777-A1 | Indane or dihydroindole derivatives | H. LUNDBECK A/S (DK) | 2001-09-13 | — | — | US | disclosed |
| CN-1079741-A | The preparation method of analgesic carboxylic acid amide derivatives | SANKYO CO (JP) | 1993-12-22 | — | — | CN | disclosed |
| CN-1079740-A | The preparation method of analgesic carboxylic acid amide derivatives | SANKYO CO (JP) | 1993-12-22 | — | — | CN | disclosed |
| CN-1078461-A | The preparation method of analgesic carboxylic acid amide derivatives | SANKYO CO (JP) | 1993-11-17 | — | — | CN | disclosed |
| CN-1022185-C | Process for preparing analgesic carboxylic acid amide derivatives | SANKYO CO (JP) | 1993-09-22 | — | — | CN | disclosed |
| US-4957914-A | ANTIDEPRESSANTS, ANXIOLYTICS, HYPOTENSIVE AGENTS | SYNTEX (U.S.A.) INC. (US) | 1990-09-18 | — | — | US | disclosed |
| CN-1040791-A | ANALGESIC CARBOXYLIC ACID AMIDE DERIVATIVES | SANKYO CO (JP) | 1990-03-28 | — | — | CN | disclosed |
| EP-0356247-A1 | Analgesic carboxylic acid amide derivatives | Sankyo Company Limited (JP) | 1990-02-28 | — | — | EP | disclosed |
| EP-0056271-B1 | CARBOXYLIC ACID ESTERS AND INSECTICIDAL AND/OR ACARICIDAL COMPOSITIONS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-05-07 | — | — | EP | disclosed |
| US-4480118-A | Carboxylic acid ester and an insecticidal and/or acaricidal composition containing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-10-30 | — | — | US | disclosed |
| EP-0056271-A2 | Carboxylic acid esters and insecticidal and/or acaricidal compositions | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-07-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010021777-A1 | Indane or dihydroindole derivatives | HTR4, GPR4, GPR174 | PIN1 944/4885KCNQ2 1095/4885IDH1 1022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.